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首页> 外文会议>Conference on Light and Optics in Biomedicine Oct 23-25, 2000, Warsaw, Poland >DIAGNOSTIC POTENTIAL OF ULTRAVIOLET LASER-INDUCED AUTOFLUORESCENCE OF STOMACH TISSUES
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DIAGNOSTIC POTENTIAL OF ULTRAVIOLET LASER-INDUCED AUTOFLUORESCENCE OF STOMACH TISSUES

机译：紫外激光诱导的胃组织自发荧光的诊断潜力

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摘要

Images of the laser-induced fluorescence (325 nm, He-Cd laser) were recorded in vitro in six regions of a visible spectrum using a cooled CCD camera. Images were taken sequentially and then processed to assess the ability of such an approach to detect and to localise cancer tissues. 72 areas of 21 resected specimens were examined. It has been established that a difference of fluorescence intensities measured at 440 nm and 395 nm, both normalised to intensity measured at 590 nm differs significantly for the neoplastic and non-neoplastic tissues of interest. Using this quantity as a diagnostic parameter it was possible to classify malignant gastric tissues with a sensitivity of 96% and a specificity of 42% while the same approach applied to abnormal stomach tissues gave respectively values of 80% and 98%.
机译：使用冷却的CCD照相机在体外在可见光谱的六个区域中记录激光诱导的荧光（325 nm，He-Cd激光）的图像。依次拍摄图像，然后进行处理，以评估这种方法检测和定位癌组织的能力。检查了21个切除标本的72个区域。已经确定，对于感兴趣的赘生性和非赘生性组织，在440nm和395nm处测量的荧光强度的差异均被标准化为在590nm处测量的强度显着不同。使用该量作为诊断参数，可以以96％的敏感性和42％的特异性对恶性胃组织进行分类，而对异常胃组织应用的相同方法得出的值分别为80％和98％。

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