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首页> 外文会议>Conference on Medical Imaging 2008: Imaging Processing; 20080217-19; San Diego,CA(US) >The SRI24 Multi-Channel Brain Atlas: Construction and Applications
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The SRI24 Multi-Channel Brain Atlas: Construction and Applications

机译：SRI24多通道脑图集：构建和应用

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摘要

We present a new standard atlas of the human brain based on magnetic resonance images. The atlas was generated using unbiased population registration from high-resolution images obtained by multichannel-coil acquisition at 3T in a group of 24 normal subjects. The final atlas comprises three anatomical channels (t_1 -weighted, early and late spin echo), three diffusion-related channels (fractional anisotropy, mean diffusivity, diffusion-weighted image), and three tissue probability maps (CSF, gray matter, white matter). The atlas is dynamic in that it is implicitly represented by nonrigid transformations between the 24 subject images, as well as distortion-correction alignments between the image channels in each subject. The atlas can, therefore, be generated at essentially arbitrary image resolutions and orientations (e.g., AC/PC aligned), without compounding interpolation artifacts. We demonstrate in this paper two different applications of the atlas: (a) region definition by label propagation in a fiber tracking study is enabled by the increased sharpness of our atlas compared with other available atlases, and (b) spatial normalization is enabled by its average shape property. In summary, our atlas has unique features and will be made available to the scientific community as a resource and reference system for future imaging-based studies of the human brain.
机译：我们提出了基于磁共振图像的人脑的新标准图集。该图集是使用24个正常受试者在3T处通过多通道线圈采集获得的高分辨率图像使用无偏差的人口配准生成的。最终的地图集包括三个解剖通道（t_1加权，早期和晚期自旋回波），三个与扩散有关的通道（分数各向异性，平均扩散率，弥散加权图像）和三个组织概率图（CSF，灰质，白质） ）。该图集是动态的，因为它由24个对象图像之间的非刚性变换以及每个对象中图像通道之间的失真校正对齐方式隐式表示。因此，可以在基本上任意的图像分辨率和方向（例如，AC / PC对齐）下生成图集，而无需复合插值伪像。我们在本文中演示了地图集的两种不同应用：（a）通过与其他可用地图集相比，地图集清晰度的提高，可以在纤维跟踪研究中通过标签传播来定义区域，以及（b）通过对其进行空间归一化平均形状特性。总而言之，我们的地图集具有独特的功能，并将作为未来基于人脑成像研究的资源和参考系统提供给科学界。

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