Characterization of the Second Harmonic Signal from Collagen

机译：胶原蛋白第二谐波信号的表征

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Collagen is known to be a very effective generator of the second harmonic of incident light from 700 to 1100nm, and second harmonic generation (SHG) microscopy is coming into use as a tool for studying the distribution of collagen in tissue. It also shows promise as a technique for characterising collagen - both in distinguishing different collagen types and their packing and in identifying degradation of collagen in pathologic conditions. However many aspects of image formation in SHG microscopy of collagen remain imperfectly understood, and we have commenced a rigorous study of these factors. The present paper presents the first results from this program.

机译：众所周知，胶原蛋白是700至1100nm入射光的二次谐波的非常有效的发生器，并且二次谐波生成（SHG）显微镜已被用作研究组织中胶原蛋白分布的工具。它还具有作为胶原蛋白表征技术的潜力-既可以区分不同的胶原蛋白类型及其堆积，也可以识别病理状况下的胶原蛋白降解。然而，胶原蛋白在SHG显微镜中成像的许多方面仍未完全了解，我们已经开始对这些因素进行严格的研究。本文介绍了该程序的第一个结果。

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来源
《Conference on Multiphoton Microscopy in the Biomedical Sciences III Jan 26-28, 2003 San Jose, California, USA》|2003年|p.32-40|共9页
会议地点 San Jose CA(US)
作者
Guy Cox; Paul Xu; Colin Sheppard; John Ramshaw;
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作者单位

Electron Microscope Unit F09, University of Sydney, NSW 2006 Australia;

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会议组织
原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
second harmonic generation; collagen; non-linear microscopy; 2-photon fluorescence; colocalization;

机译：二次谐波胶原非线性显微镜二光子荧光共定位;

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机译：胶原蛋白二次谐波信号的表征

Characterization of the Second Harmonic Signal from Collagen

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