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A novel method of using hollow-core photonic crystal fiber as a Raman biosensor

机译:使用空心光子晶体光纤作为拉曼生物传感器的新方法

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摘要

A new method for using a non-selectively filled hollow-core photonic crystal fiber (HC-PCF) as a sensitive Raman spectroscopy platform suitable for biosensing applications is presented. A 1550 HC-PCF was completely filled with ethanol (core and cladding holes). Using a 785nm excitation laser, the Raman spectrum of ethanol in the fiber core was obtained and compared with the equivalent Raman spectrum of an ethanol-filled cuvette. Using a relatively short 9.5cm length of HC-PCF, a Raman signal enhancement factor of 40 over a bulk solution of ethanol was observed under the same excitation conditions. The small sample volume utilized and longer interaction length provides the potential for compact, sensitive, and low-power Raman sensing of biological materials
机译:提出了一种使用非选择性填充的空心光子晶体光纤(HC-PCF)作为适用于生物传感应用的敏感拉曼光谱平台的新方法。 1550 HC-PCF完全充满了乙醇(芯孔和包层孔)。使用785nm激发激光,获得了纤维纤芯中乙醇的拉曼光谱,并将其与乙醇填充比色皿的等效拉曼光谱进行了比较。使用相对较短的9.5cm长的HC-PCF,在相同的激发条件下,观察到在大量乙醇溶液中拉曼信号增强因子为40。利用的样品量少,相互作用时间长,为生物材料的紧凑,灵敏和低功耗拉曼传感提供了潜力

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