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首页> 外文会议>Conference on Novel Optical Instrumentation for Biomedical Applications; Jun 24-25, 2003; Munich, Germany >Effects of prior MRI information on image reconstruction in diffuse optical tomography
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Effects of prior MRI information on image reconstruction in diffuse optical tomography

机译：先前的MRI信息对弥散光学层析成像中图像重建的影响

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摘要

We describe a method to increase the speed of convergence for the simultaneous reconstruction of absorption and scattering images in Diffuse Optical Tomography (DOT). We used the diffusion approximation of the radiative transfer equation and the Finite Element Method (FEM) to solve the forward problem. The absorption and reduced scattering images are reconstructed by inverting the distribution of the moments of the time-dependent detected light flux. The inverse problem is solved with an optimization algorithm like ART or Conjugate Gradient. This ill-posed inverse problem can be simplified by using a priori knowledge of the studied objects. In this paper, we consider that DOT is a functional imaging technique that can be complemented by an anatomical imaging technique like Magnetic Resonance Imaging (MRI). We used anatomic information obtained from MRI as prior knowledge to compute optical absorption and scattering images. In a first step, MRI segmented images were only used to mesh our phantoms, with a finer resolution around boundaries. In a second step, we computed optical images with homogeneous properties from the segmented MRI image, in order to initialise our optimisation process. These two initialisations yield better reconstructed images. Reconstruction from simulated and experimental data will be presented.
机译：我们描述了一种方法，以提高在扩散光学层析成像（DOT）中同时重建吸收和散射图像的收敛速度。我们使用辐射传递方程的扩散近似和有限元方法（FEM）解决了前向问题。通过反转与时间有关的检测光束的矩的分布，可以重建吸收和减少的散射图像。反问题可以通过优化算法（例如ART或共轭梯度）来解决。不适定的逆问题可以通过使用研究对象的先验知识来简化。在本文中，我们认为DOT是一种功能成像技术，可以通过诸如磁共振成像（MRI）之类的解剖学成像技术来补充。我们使用从MRI获得的解剖学信息作为先验知识来计算光吸收和散射图像。第一步，MRI分割后的图像仅用于对我们的体模进行网格划分，并具有更好的边界分辨率。第二步，我们从分割的MRI图像中计算出具有均一性质的光学图像，以初始化我们的优化过程。这两个初始化产生更好的重建图像。将介绍从模拟和实验数据进行的重建。

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