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首页> 外文会议>Conference on Optical Biopsy and Tissue Optics 5-6 July 2000 Amsterdam, the Netherlands >Broadly tunable optical harmonic generation in type I collagen using IR nanosecond laser pulses
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Broadly tunable optical harmonic generation in type I collagen using IR nanosecond laser pulses

机译：使用IR纳秒激光脉冲在I型胶原蛋白中产生可广泛调谐的光谐波

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摘要

Under pulsed nanosecond laser irradiation of type I pure collagen over the 760-1070 nm spectral range, optical upconversion of the incident radiaiton is observed. More specifically irradiation of collagen at 1064, 901, 892, 828, 785 and 766 nm produces monochromatic second harmonic signals at half the original wavelengths i.e. 532, 451, 446, 414, 393 and 383nm respectively. The dependence of the second harmonic signal on the excitation intensity was found to be quadratic (log(I_(532))=1.92*log(I_(1064)). A weaker third harmonic signal was also observed from collagen at 355nm when irradiated by 1064nm nanosecond pulses. This signal was found to bear a near cubic dependence upon the irradiation intensity (log(I_(356))=2.53*log(I_(1064)). The polar distribution of the second harmonic radiation was recorded for both pure fibrous collagen as well as for collagen diluted in acetic acid and forming a semitransparent dry film. In the latter case, significant optical behavior was demonstrated, potentially important for further studies of these nonlinear phenomena and for novel applications.
机译：在760-1070 nm光谱范围内的I型纯胶原的脉冲纳秒激光辐照下，观察到入射辐射的光学上转换。更具体地说，在1064、901、892、828、785和766nm处辐照胶原蛋白会在原始波长的一半即分别为532、451、446、414、393和383nm处产生单色二次谐波信号。发现二次谐波信号对激发强度的依赖性是二次的（log（I_（532））= 1.92 * log（I_（1064））。当在355nm处被胶原照射时，还观察到较弱的三次谐波信号。 1064nm纳秒脉冲，发现该信号与辐照强度几乎呈立方关系（log（I_（356））= 2.53 * log（I_（1064））。记录了两种纯净的二次谐波辐射的极性分布纤维状胶原蛋白，以及在乙酸中稀释并形成半透明干膜的胶原蛋白，在后一种情况下，表现出显着的光学行为，对于进一步研究这些非线性现象和新应用具有潜在的重要性。

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