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Study of the Pressure Effect in Near-Infrared Spectroscopy

机译:近红外光谱中压力效应的研究

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摘要

It has been observed for a long time that the compressive pressure applied on the tissue significantly effects the measurement of Near-Infrared Spectroscopy. The clinical study implies a certain level of correlation between the tissue type and its response to pressure. However, this correlation is not quite understood nor quantified yet, especially in the diffuse optical imaging arena. This paper discusses the development of NIRS tissue spectrometer with real time pressure monitoring and a series of pressure regulated experiments we have conducted on human subjects. By analyzing the pattern of the 2D mapping of tissue hemoglobin concentration and oxygen saturation in response to the temporal profile of the compression force, we are able to explore major factors that influence the pressure regulated measurement
机译:长期以来观察到施加在组织上的压缩压力显着影响近红外光谱的测量。临床研究表明组织类型与其对压力的反应之间存在一定程度的相关性。然而,这种相关性还没有被完全理解或量化,特别是在漫射光学成像领域。本文讨论了具有实时压力监测功能的NIRS组织光谱仪的开发以及我们在人体上进行的一系列压力调节实验。通过分析组织血红蛋白浓度和氧饱和度响应压力变化的二维映射模式,我们能够探索影响压力调节测量的主要因素

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