Complex Flow Characterisation of a Porous Tissue Scaffold Measured by Doppler Optical Coherence Tomography

机译：多普勒光学相干断层扫描测量的多孔组织支架的复杂流动特性。

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The flow of culture medium through a mechanically stimulated cell-seeded tissue scaffold is a factor influencing not only the transport of essential nutrients and waste product removal but also impacting on the degradation kinetics of the scaffold. Being able to map spatial and temporal changes in fluid flow behaviour is key to the development of improved bioreactors and tissue scaffold designs, especially for the new generation of multiple tissue reactors. In this paper we demonstrate the excellent metrological benefits of fast Doppler optical coherence tomography for time-lapse characterisation of tissue scaffolds placed in a dynamic flow environment.

机译：培养基通过机械刺激的接种有细胞的组织支架的流动不仅是必需营养素的运输和废物的去除的影响因素，而且还影响支架的降解动力学。能够绘制出流体流动行为的时空变化图，对于开发改进的生物反应器和组织支架设计至关重要，特别是对于新一代的多组织反应器而言。在本文中，我们证明了快速多普勒光学相干断层扫描技术在动态流动环境中对组织支架的延时表征方面的卓越计量优势。

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来源
《Conference on Optics in Tissue Engineering and Regenerative Medicine; 20080120-21; San Jose,CA(US)》|2008年|P.iviii|共2页
会议地点 San JoseCA(US)
作者
Peter H. Tomlins; Yiwei Wang; Bufa Zhang; Matthew Tedaldi; Paul E. Tomlins;
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作者单位

Optical Technologies Group, National Physical Laboratory, Hampton Road, Teddington, Middlesex, TW11 0LW, UK;

Biomaterials Group, National Physical Laboratory, Hampton Road, Teddington, Middlesex, TW11 0LW, UK;

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原文格式 PDF
正文语种 eng
中图分类医用物理学;
关键词
doppler optical coherence tomography; complex flow; tissue scaffolds; tissue engineering; regenerative medicine;

机译：多普勒光学相干断层扫描；复杂流；组织支架；组织工程；再生医学;

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2. Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography [J] . Alex D. Pechauer, Ou Tan, Liang Liu, Investigative ophthalmology & visual science . 2016,第9期

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3. Total retinal blood flow in healthy and glaucomatous human eyes measured with 3 beam Doppler optical coherence tomography [J] . Haindl Richard, Wartak Andreas, Trasischker Wolfgang, Investigative ophthalmology & visual science . 2016,第12期

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4. Complex Flow Characterisation of a Porous Tissue Scaffold Measured by Doppler Optical Coherence Tomography [C] . Peter H. Tomlins, Yiwei Wang, Bufa Zhang, Conference on Optics in Tissue Engineering and Regenerative Medicine . 2008

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5. Cystoscopic Optical Coherence Tomography and Ultrahigh Resolution Optical Doppler Tomography for Quantitative Structural and Functional Imaging [D] . Ren, Hugang. 2012

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6. Longitudinal Changes in Retinal Blood Flow in a Feline Retinal Vein Occlusion Model as Measured by Doppler Optical Coherence Tomography and Optical Coherence Tomography Angiography [O] . Takanari Wada, Youngseok Song, Tsuneaki Oomae, -1

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Complex Flow Characterisation of a Porous Tissue Scaffold Measured by Doppler Optical Coherence Tomography

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