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首页> 外文会议>Conference on Photon Migration and Diffuse - Light Imaging; Jun 22-23, 2003; Munich, Germany >Three-dimensional localization of fluorescence spots with adapted MUSIC algorithm
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Three-dimensional localization of fluorescence spots with adapted MUSIC algorithm

机译：自适应MUSIC算法对荧光点进行三维定位

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摘要

We present a novel method, space-space MUSIC (Multiple Signal Classification), to localize three-dimensionally focal fluorophore-tagged lesions activated subsequently by different laser source positions from multi-sensor fluorescence data obtained from a single measurement plane. Matches between a signal subspace derived from the measured data and data from model spots allow 3D determination of the centers-of-gravity of fluorescence regions. Simulated spots in bounded, inhomogeneous media could be localized accurately. The algorithm has shown to be robust against patient-dependent parameters, such as optical background parameters. The algorithm does also not consider medium boundaries.
机译：我们提出了一种新的方法，空间-空间MUSIC（多信号分类），以定位三维聚焦荧光标记的病变，这些病变随后由来自单个测量平面的多传感器荧光数据中的不同激光源位置激活。从测得的数据得出的信号子空间与模型点的数据之间的匹配可以对荧光区域的重心进行3D确定。有界，非均质介质中的模拟斑点可以准确定位。该算法已证明对依赖于患者的参数（例如光学背景参数）具有鲁棒性。该算法也没有考虑中等边界。

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