Functional brain imaging by CW-NIRS coregistered by blood flow monitors

机译：血流监测仪通过CW-NIRS进行的功能性脑成像

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摘要

Since a functional near-infrared spectroscopy monitor is a small and flexible tool, it can well be integrated with blood flow monitors. In the first part of the publication we show, that laser-doppler-flow measurements on the scalp return stimulus induced blood-volume changes. The effect of these changes on CW-NIRS measurements is demonstrated using frequency-domain-system capable of distinguishing absorption changes in superficial layers from those in the bulk tissue. The relationship between cerebral blood flow and cerebral hemoglobin concentration is studied in the second part of the publication. We present a visual stimulation experiment where changes in posterior cerebral artery flow velocity (PCA-Fv) were continuously monitored bilaterally by transcranial doppler sonography. Combining this approach with CW-NIRS imaging shows that the change in the arterial blood flow velocity occur approximately 1s before the deoxy-hemoglobin changes.

机译：由于功能性近红外光谱监视器是一种小型且灵活的工具，因此可以很好地与血流监视器集成在一起。在出版物的第一部分中，我们显示了对头皮返回刺激的激光多普勒血流测量引起的血容量变化。这些变化对CW-NIRS测量的影响已通过使用频域系统得到了证明，该系统能够区分浅层吸收变化与大块组织吸收变化。该出版物的第二部分研究了脑血流量与脑血红蛋白浓度之间的关系。我们提出了一种视觉刺激实验，通过经颅多普勒超声对双侧大脑后动脉流速（PCA-Fv）的变化进行连续监测。将该方法与CW-NIRS成像相结合，表明在脱氧血红蛋白改变之前大约1 s发生了动脉血流速度的改变。

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来源
《Conference on Photon Migration and Diffuse - Light Imaging; Jun 22-23, 2003; Munich, Germany》|2003年|p.131-138|共8页
会议地点 Munich(DE)
作者
J. Steinbrink; F. Kempf; S. Schreiber; K. Uludag; M. Kohl; J. M.Valdueza; A. Villringer; H.Obrig;
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作者单位

Neurolgical Dept. at the Universityhospital Charite, Schumannstr. 20/21, 10098 Berlin, Germany;

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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
MRS of the brain; extra-cerebral effects; ultra-sound-doppler; perfusion;

机译：脑MRS;脑外影响;超声多普勒;灌注;

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Functional brain imaging by CW-NIRS coregistered by blood flow monitors

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