Functional imaging system for simultaneous measurement of blood volume and flow

机译：功能成像系统，可同时测量血容量和流量

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摘要

Optical imaging derived from intrinsic signals such as blood volume and flow has enabled us to characterize the area of brain activation. Multi-spectral imaging of the change in cortical reflectance allows the determination of the change in the oxy-hemoglobin concentration independent of the deoxy-haemoglobin concentration. The changes in blood volume and oxygenation are closely related to the cerebral blood flow, and hence the simultaneous measurement of blood volume and flow in the cortical tissue must be beneficial for investigation of functional brain activation. Laser speckle flowgraphy has also been developed to visualize the blood flow in tissue and has been applied to measure the blood flow in tissue. In this study, a functional imaging system has been designed and assembled for the simultaneous measurement of the change in blood volume and flow in tissue. The optical systems of multi-spectral imaging and laser speckle flowgraphy are attached to the photo ports of the beam-splitter attachment of a stereo-microscope. The data of the multi-spectral image and speckle pattern of phantoms and finger are obtained for the initial experiments with the proposed system.

机译：从内在信号（例如血容量和血流）得出的光学成像使我们能够表征大脑激活的区域。皮层反射率变化的多光谱成像允许确定氧合血红蛋白浓度的变化，而与脱氧血红蛋白浓度无关。血容量和氧合的变化与脑血流量密切相关，因此同时测量皮层组织中的血容量和血流量对于研究脑功能激活必不可少。还已经开发了激光散斑流描法以可视化组织中的血流，并且已经被用于测量组织中的血流。在这项研究中，已经设计并组装了功能成像系统，用于同时测量血液量和组织流量的变化。多光谱成像和激光散斑成像的光学系统连接到立体显微镜的分束器附件的光端口。该系统的初始实验获得了幻影和手指的多光谱图像和斑点图案的数据。

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来源
《Conference on Photon Migration and Diffuse - Light Imaging; Jun 22-23, 2003; Munich, Germany》|2003年|p.231-238|共8页
会议地点 Munich(DE)
作者
Yohei Watanabe; Hitoshi Fujii; Eiji Okada;
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作者单位

Department of Electronics and Electrical Engineering, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama, 223-8522, Japan;

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会议组织
原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
functional imaging; multi-spectral imaging; laser speckle flowgraphy; blood volume; blood flow;

机译：功能成像;多光谱成像;激光散斑成像;血量;血流;

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4. Functional imaging system for simultaneous measurement of blood volume and flow [C] . Yohei Watanabe, Hitoshi Fujii, Eiji Okada Conference on photon migration and diffuse-light imaging . 2003

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Functional imaging system for simultaneous measurement of blood volume and flow

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