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首页> 外文会议>Conference on Physiology and Function: Methods, Systems, and Applications Feb 16-18, 2003 San Diego, California, USA >Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators
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Experimental studies of SPECT scintimammography with combined cone-beam and parallel-beam collimators

机译：锥束与平行束准直仪组合的SPECT乳腺X线摄影的实验研究

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摘要

Conventional SPECT Tc-99m sestamibi scintimammography (STSM) has limited clinical utility due to fairly low radiopharmaceutical uptake in the breast tissue as compared to the heart and the liver. We investigated the use of a cone-beam collimator (CBC) to STSM. Each detector on a multi-headed gamma camera can be equipped with parallel-beam (PBC) or cone-beam collimators (CBC). PBC can provide truncation-free SPECT projection sets, while CBC offers increased sensitivity in a limited field-of-view (FOV). Combined PBC and CBC SPECT data acquisition may provide improved lesion contrast and overall better imaging performance within CBC FOV with significantly reduced truncation artifacts in the reconstructed images. In this paper we evaluate the combined CBC&PBC SPECT method using a limited number of confirmed breast cancer patients and female chest phantoms with simulated breast lesions. We envision the combined CBC&PBC SPECT as a useful clinical tool in scintimammography.
机译：由于与心脏和肝脏相比，乳腺组织中相当低的放射性药物吸收，常规的SPECT Tc-99m西斯塔米比闪烁成像（STSM）具有有限的临床实用性。我们研究了对STSM使用锥形束准直器（CBC）。多头伽马相机上的每个探测器都可以配备平行光束（PBC）或锥形光束准直仪（CBC）。 PBC可以提供无截断的SPECT投影集，而CBC可以在有限的视场（FOV）中提供更高的灵敏度。结合的PBC和CBC SPECT数据采集可以在CBC FOV内提供改善的病变对比度和总体上更好的成像性能，并显着减少重建图像中的截断伪像。在本文中，我们评估了有限的确诊乳腺癌患者和具有模拟乳腺病变的女性胸模的CBC＆PBC SPECT组合方法。我们设想将CBC＆PBC SPECT结合起来作为闪烁X线照相术中的有用临床工具。

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