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首页> 外文会议>Conference on X-Ray and Gamma-Ray Detectors and Applications IV, Jul 7-9, 2002, Seattle, Washington, USA >Design and characterization of a large-area, lens-coupled CCD detector for macromolecular crystallography
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Design and characterization of a large-area, lens-coupled CCD detector for macromolecular crystallography

机译：用于大分子晶体学的大面积透镜耦合CCD检测器的设计与表征

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摘要

We have prototyped and characterized a very large format X-ray detector for macromolecular crystallography. The X-ray field strength is converted to visible light in a phosphor film. Light from the phosphor is focused onto a CCD imager by a lens specially designed for this detector, that has a very high numerical aperture. The CCD is very large (61 mm, 4,096x4,096 pixels), and employs a very low-noise on-chip preamplifier. Lens coupling between phosphor film and CCD avoids many of the optical imperfections of fiber optic coupling, but it remains a challenge to make a lens system with optical transfer efficiency matching or exceeding that of fiber optical systems. We have met this challenge by enhancing system gain in our detector through implementation of modern lens technologies and imaginative CCD design. At this point the system gain equals that of conventional CCD-based X-ray crystallography detectors, which couple the CCD to the phosphor through a fiber optic taper. Although many of our technical developments could also be used in fiber optic detectors, the overriding virtues of the lens-coupled detector are simplicity, optical perfection, and cost.
机译：我们已经为大型分子晶体学设计了一个非常大型的X射线探测器，并对其进行了原型设计。 X射线场强度在荧光膜中转换为可见光。荧光粉发出的光通过专门为该检测器设计的透镜聚焦到CCD成像仪上，该透镜具有很高的数值孔径。 CCD非常大（61毫米，4,096x4,096像素），并采用了非常低噪声的片上前置放大器。磷光体膜和CCD之间的透镜耦合避免了光纤耦合的许多光学缺陷，但是要使透镜系统的光学传输效率与光纤光学系统相匹配或超越，仍然是一个挑战。我们通过实施现代镜头技术和富有想象力的CCD设计来提高探测器的系统增益，从而应对了这一挑战。在这一点上，系统增益等于传统的基于CCD的X射线晶体学检测器，后者通过光纤锥将CCD耦合到磷光体。尽管我们的许多技术发展也可以用于光纤检测器，但透镜耦合检测器的主要优点是简单，光学完美和成本高。

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