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Personalized Medicine and the Need for Decision Support Systems

机译：个性化医学与决策支持系统的需求

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Advances in genomics and human genetics have enabled a more detailed understanding of the impact of genetics in a disease and its treatment. In addition to a patient's clinical signs and symptoms, physicians can now or in near future consider genetic data for their diagnosis and treatment decisions. This new information source based on genome and gene expression analysis makes clinical decision processes even more complex. Beyond, behavioral and environmental aspects should also be considered in order to realize personalized medicine. Given these additional information sources, the need for support in decision making is increasing. In this paper, we introduce a vision how knowledge-based systems or decision support systems can help to realize personalized medicine and we explore the upcoming challenges for clinical decision support in that context.
机译：基因组学和人类遗传学的进步使人们对遗传学在疾病及其治疗中的影响有了更详细的了解。除了患者的临床体征和症状外，医生现在或不久的将来还可以考虑遗传数据以进行诊断和治疗决策。这种基于基因组和基因表达分析的新信息源使临床决策过程变得更加复杂。除此之外，还应考虑行为和环境因素，以实现个性化医学。有了这些额外的信息来源，决策支持的需求在增加。在本文中，我们介绍了一种基于知识的系统或决策支持系统如何帮助实现个性化医学的愿景，并且我们将探讨在这种情况下临床决策支持所面临的挑战。

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