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Time-resolved diffuse optical spectroscopy of small tissue samples

机译:小组织样品的时间分辨漫射光谱

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Time-resolved transmittance measurements were performed in the wavelength range of 610 or 700 to 1050 nm on phantom slabs and bone tissue cubes of different sizes. The data were best fitted with solutions of the diffusion equation for an infinite slab and for a parallelepiped to investigate how size and optical properties of the samples affect the results obtained with the two models. When small samples are considered, the slab model overestimates both optical coefficients, especially the absorption. The parallelepiped model largely compensates for the small sample size and performs much better also when the absorption spectra are interpreted with the Beer's law to estimate bone tissue composition.
机译:在不同尺寸的体模平板和骨组织立方体上,在610或700至1050 nm的波长范围内进行了时间分辨的透射率测量。数据最适合无穷平板和平行六面体扩散方程的解,以研究样品的尺寸和光学性质如何影响通过两个模型获得的结果。当考虑小样本时,平板模型会高估两个光学系数,尤其是吸收率。平行六面体模型在很大程度上弥补了样本量的不足,并且在用比尔定律解释吸收光谱以估算骨组织组成时,其性能也要好得多。

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