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Time-domain diffuse optics: towards next generation devices

机译：时域漫射光学：面向下一代设备

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摘要

Diffuse optics is a powerful tool for clinical applications ranging from oncology to neurology, but also for molecular imaging, and quality assessment of food, wood and pharmaceuticals. We show that ideally time-domain diffuse optics can give higher contrast and a higher penetration depth with respect to standard technology. In order to completely exploit the advantages of a time-domain system a distribution of sources and detectors with fast gating capabilities covering all the sample surface is needed. Here, we present the building block to build up such system. This basic component is made of a miniaturised source-detector pair embedded into the probe based on pulsed Vertical-Cavity Surface-Emitting Lasers (VCSEL) as sources and Single-Photon Avalanche Diodes (SPAD) or Silicon Photomultipliers (SiPM) as detectors. The possibility to miniaturized and dramatically increase the number of source detectors pairs open the way to an advancement of diffuse optics in terms of improvement of performances and exploration of new applications. Furthermore, availability of compact devices with reduction in size and cost can boost the application of this technique.
机译：漫射光学是一种强大的工具，可用于从肿瘤学到神经病学的临床应用，还可以用于分子成像以及食品，木材和药品的质量评估。我们表明，相对于标准技术，理想情况下，时域漫射光学器件可以提供更高的对比度和更高的穿透深度。为了充分利用时域系统的优点，需要具有覆盖所有样品表面的快速选通功能的源和检测器的分布。在这里，我们介绍构建此类系统的基础。该基本组件由嵌入到探头中的一对微型源探测器组成，该探测器对基于脉冲垂直腔表面发射激光器（VCSEL）作为源，而单光子雪崩二极管（SPAD）或硅光电倍增管（SiPM）作为探测器。小型化和大幅增加源探测器对数量的可能性为提高性能和探索新应用开辟了漫射光学技术的发展之路。此外，减小尺寸和成本的紧凑设备的可用性可以促进该技术的应用。

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  • 来源
    《Diffuse optical imaging V》|2015年|95380A.1-95380A.4|共4页
  • 会议地点 Munich(DE)
  • 作者

    Davide Contini; Alberto Dalla Mora; Simon Arridge; Fabrizio Martelli; Alberto Tosi; Gianluca Boso; Andrea Farina; Turgut Durduran; Edoardo Martinenghi; Alessandro Torricelli; Antonio Pifferi;

  • 作者单位

    Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK;

    Dipartimento di Fisica e Astronomia, Universita degli Studi di Firenze, Via G. Sansone 1, 50019 Sesto Fiorentino, Firenze, IT;

    Dipartimento di Elettronica Informazione e Bioingegneria, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Dipartimento di Elettronica Informazione e Bioingegneria, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Istituto di Fotonica e Nanotecnologie, CNR, Piazza L. da Vinci 32, 20133 Milano, IT;

    ICFO-Institut de Ciencies Fotoniques, Mediterranean Technology Park, 08860 Castelldefels (Barcelona), ES;

    Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT;

    Dipartimento di Fisica, Politecnico di Milano, Piazza L. da Vinci 32, 20133 Milano, IT,Istituto di Fotonica e Nanotecnologie, CNR, Piazza L. da Vinci 32, 20133 Milano, IT;

  • 会议组织
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Time Resolved Diffuse Optics; Photon Migration; SPAD; SiPM;

    机译：时间分辨漫射光学；光子迁移； SPAD；硅橡胶;

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