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Cross-Calibration and Longitudinal Quality Control ofHologic Selenia Full-Field Digital Mammography Systems for Volumetric Breast Density Measurements

机译:Heleton Selenia全场数字化乳腺X线摄影系统的交叉校准和纵向质量控制,可用于容积性乳房密度测量

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High breast tissue density has been shown to be one of the strongest predictors of breast cancer risk in women; though currently there are no calibrated methods to ensure that clinical measures of density are accurate. This inability to make accurate measurements impedes the use of breast tissue density as a cancer risk indicator. An accurate and precise method to measure the volumetric density of breast tissue in a clinical environment has been developed without modifying existing methods. The single x-ray absorptiometry (SXA) approach is validated against known breast fibroglandular density test phantoms and the accuracy and precision of the measure is monitored longitudinally. With cross-calibration and longitudinal quality control using the same test phantoms we show that SXA density measures are comparable between seven Hologic Selenia Full-Field Digital Mammography systems. In the future, we plan to address whether SXA measures can be generalized across different makes and models.
机译:高乳房组织密度已被证明是女性罹患乳腺癌风险的最强预测因子之一。尽管目前没有校准的方法可以确保密度的临床测量准确。这种无法进行精确测量的方法阻碍了将乳腺组织密度用作癌症风险指标。在不修改现有方法的情况下,已经开发出一种在临床环境中测量乳房组织体积密度的精确方法。针对已知的乳腺纤维腺密度测试体模验证了单X射线吸收法(SXA)的方法,并纵向监测了该测量的准确性和精确性。通过使用相同的测试体模进行交叉校准和纵向质量控制,我们表明SXA密度测量值在七个Hologic Selenia全视野数字乳腺摄影系统之间是可比的。将来,我们计划解决是否可以将SXA措施推广到不同品牌和型号的情况。

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