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Global Effect and Prevention of Emerging and Epidemic Pathogens: Cholera and Citrus Greening as Examples

机译:新兴效应和流行病原体的全球影响和预防:以霍乱和柑橘绿化为例

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Emerging and epidemic infectious diseases have had a major effect on human history. We are just now coming to appreciate the mechanisms by which new strains emerge and the factors that permit their rapid spread within human populations. Cholera is a classic epidemic disease that causes periodic pandemics (possibly reflecting genetic changes in surface antigens of the microorganism) and seasonal epidemics that appear to be triggered by environmental factors. Citrus greening is a plant disease that kills citrus trees; a vector-borne bacterial disease, it is currently spreading rapidly across Florida. Control of these and other epidemic and emerging diseases may be difficult, particularly if the infection is already widespread in target populations. Any chance of successful control requires a comprehensive understanding of the pathogenesis and transmission pathways of the microorganism.
机译:新兴和流行性传染病已对人类历史产生重大影响。我们现在才开始认识到新菌株出现的机制,以及使它们在人群中迅速传播的因素。霍乱是一种典型的流行病,会引起周期性的大流行(可能反映了微生物表面抗原的遗传变化)和季节性流行,这些流行似乎是由环境因素触发的。柑橘绿化是一种杀死柑橘树的植物病。它是一种媒介传播的细菌性疾病,目前正在佛罗里达州迅速传播。控制这些以及其他流行病和新出现的疾病可能很困难,尤其是如果感染已经在目标人群中传播的话。成功控制的任何机会都需要全面了解微生物的发病机理和传播途径。

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