New developments in two photon endoscopy

机译：两种光子内窥镜的新发展

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We designed and constructed a two-fiber-optic two-photon endoscope with compact two axes piezo scanner system and a miniature high 0.65 NA Grin lens objective. The high NA GRIN lens objective coupled to the fibers with a beam splitter cube represent a rigid miniaturized optical system block which is scanned as a whole by a piezo scanner allowing always an on-axes beam irradiation of the optical system. We have demonstrated the ability of our system to perform good images in the micrometer field. Fluorescence detection was able at different wavelengths between 790 and 840 nm which could allow SHG detection. The endoscope is high flexible and controllable in terms of time acquisition, resolution and magnification. Fluorescence images were acquired over a maximal 420 μm × 420 μm field-of-view.

机译：我们设计并制造了带有紧凑型两轴压电扫描仪系统和微型高0.65 NA Grin透镜物镜的双光纤双光子内窥镜。通过分束器立方体耦合到光纤的高NA GRIN透镜物镜代表了一种刚性的小型光学系统模块，该模块通过压电扫描仪进行整体扫描，从而始终对光学系统进行轴上光束照射。我们已经证明了我们的系统能够在微米范围内执行良好图像的能力。荧光检测能够在790至840 nm之间的不同波长进行，这可以进行SHG检测。内窥镜在时间获取，分辨率和放大倍数方面具有很高的灵活性和可控性。在最大420μm×420μm的视野范围内采集荧光图像。

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来源
《Endoscopic microscopy IV》|2009年|717204.1-717204.9|共9页
会议地点 San Jose CA(US)
作者
M. Schwarz; I. Riemann; M. Weinigel; K. Koenig; B. Messerschmidt; R. Le Harzic;
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作者单位

Fraunhofer Institute of Biomedical Technology, Ensheimer Strasse 48, 66386 St. Ingbert, Germany;

Fraunhofer Institute of Biomedical Technology, Ensheimer Strasse 48, 66386 St. Ingbert, Germany;

JenLab GmbH, Schillerstrasse 1, 07745 Jena, Germany;

JenLab GmbH, Schillerstrasse 1, 07745 Jena, Germany;

Grintech GmbH, Schillerstrasse 1, 07745 Jena, Germany;

Fraunhofer Institute of Biomedical Technology, Ensheimer Strasse 48, 66386 St. Ingbert, Germany;

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原文格式 PDF
正文语种 eng
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关键词
GRIN-lens; two-photon; endoscope; PCF; piezo-scanner;

机译：GRIN镜头两光子内窥镜PCF;压电扫描仪;

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2. Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion [J] . Kochhar Rakesh, Ashat Munish, Reddy Yalaka Rami, Endoscopy: Journal for Clinical Use Biopsy and Technique . 2017,第7期

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3. Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion [J] . Quenerve L. Endoscopy: Journal for Clinical Use Biopsy and Technique . 2017,第7期

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4. New developments in two photon endoscopy [C] . M. Schwarz, I. Riemann, M. Weinigel, Conference on endoscopic microscopy . 2009

机译：两个光子内窥镜检查的新发展
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New developments in two photon endoscopy

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