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Factors Influencing Pesticide Risks for Children

机译:影响儿童农药风险的因素

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摘要

Infants and young children constitute a particular population of concern in terms of exposure to pesticides (including obsolete pesticides). For various reasons (behavioral, anatomical and metabolic) children may have greater susceptibility to the adverse effects of pesticide exposure. This potential for increased susceptibility must be evaluated on a case-by-case basis however, because in some cases children (particularly older children) may have similar or even less susceptibility compared to adults. Research has also pointed out a number of toxicological modes of action that may be of particular relevance for children's health risks. These include effects on nervous system maturation, endocrine disruption and the influence of early life exposures on development of disease later in life. Although the importance of such modes of action is not yet fully understood, particularly at low levels of exposure, these are areas of expanding research and the data obtained are expected to be useful for improving health risk assessment in this population.
机译:就接触农药(包括过时的农药)而言,婴儿和幼儿是一个特殊的关注人群。由于各种原因(行为,解剖和代谢方面的原因),儿童可能更容易受到农药暴露的不利影响。但是,必须根据具体情况评估这种易感性增加的可能性,因为在某些情况下,儿童(尤其是年龄较大的儿童)与成年人相比可能具有相似甚至更低的易感性。研究还指出了许多可能与儿童健康风险特别相关的毒理作用方式。这些包括对神经系统成熟,内分泌干扰的影响,以及早期生活暴露对晚年疾病发展的影响。尽管尚未充分了解此类作用方式的重要性,尤其是在低暴露水平下,但这些是正在扩展的研究领域,预计获得的数据可用于改善该人群的健康风险评估。

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