首页> 外文会议>European conference on biomaterials >Calcium phosphate nanoparticles carrying BMP-7 plasmid DNA induce osteogenic differentiation in MC3T3-E1 pre-osteoblasts
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Calcium phosphate nanoparticles carrying BMP-7 plasmid DNA induce osteogenic differentiation in MC3T3-E1 pre-osteoblasts

机译:携带BMP-7质粒DNA的磷酸钙纳米颗粒诱导MC3T3-E1前成骨细胞分化为成骨细胞

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摘要

Successful transfection of MC3T3 cells with CaP NPs functionalised with BMP-7-encoding DNA, led to expression of hBMP-7 and an enhanced osteogenic response. This indicates the potential of the NPs to be used as DNA carrier materials to enhance bone formation.
机译:成功地用编码BMP-7的DNA功能化的CaP NPs转染MC3T3细胞,导致hBMP-7的表达和成骨反应增强。这表明NP被用作DNA载体材料以增强骨形成的潜力。

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