• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Fifth Asia International Symposium on Mechatronics >Integrated structuraland control design of a piezoelectric printhead for cell printing
【24h】

Integrated structuraland control design of a piezoelectric printhead for cell printing

机译：单元打印压电打印头的集成结构和控制设计

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The development of cell printing is vital for establishing bio-fabrication approaches as a tool of the organ transplantation and tissue regeneration. Though some cell printing experiments show the feasibility of this idea, however, undesired satellite droplets, nozzle clogging and cell damage in jetting process are still open issues that prevent the application of cell printing in engineering. To solve these problems, an integrated design of structural and control parameters of a piezoelectric drop-on-demand (DOD) printhead used for cell printing has been proposed. Based on the Computational-Fluid-Dynamics (CFD) model of the printhead, the desired droplet feature such as certain droplet speed and single droplet is obtained by optimizing the printhead dimensions and the control parameters, thus jetting failure and satellite droplets avoided. Moreover, the stress experienced by cells is reduced via minimizing pressure amplitude in the printhead. The results show that the optimized printhead can jet out highly viscous droplets with a desired speed and meanwhile the pressure amplitude is reduced by 15% as that it was, thus increasing the cell viability by 5.8%.
机译：细胞印刷的发展对于建立生物制造方法作为器官移植和组织再生的工具至关重要。尽管一些细胞印刷实验证明了该想法的可行性，但是，不希望的卫星液滴，喷嘴堵塞和喷射过程中的细胞损伤仍然是未解决的问题，阻碍了细胞印刷在工程中的应用。为了解决这些问题，已经提出了用于单元打印的压电按需滴落（DOD）打印头的结构和控制参数的集成设计。基于打印头的计算流体动力学（CFD）模型，可通过优化打印头尺寸和控制参数来获得所需的墨滴特征（如特定的墨滴速度和单个墨滴），从而避免喷射故障和避免卫星墨滴。而且，通过使打印头中的压力幅度最小化，可以减少单元所承受的压力。结果表明，优化的打印头可以以期望的速度喷射出高粘度的液滴，同时压力幅度按原样降低了15％，从而使细胞活力提高了5.8％。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号