THE METHOD OF MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY (MALDI- MS) AND ITS APPLICATION IN BIOANALYSIS

机译：矩阵辅助激光解吸电离质谱法（MALDI-MS）及其在生物分析中的应用

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The instrument used in the experiments is briefly described. It is a laboratory built laser microprobe time-of-flight mass spectrometer, which works both in linear mode and reflectron mode with resolution of 650 and 1350. A frequency doubled, trippled and quadrupled Nd:YAG laser is used, which provides wavelength of 266, 355, 553 and 1064 nm for selection. The laser beam is focused to a diameter of 10 or 100 um with coaxial viewing system. A sensitivity of subpicomole level is generally obtained.

机译：简要介绍了实验中使用的仪器。它是实验室制造的激光微探针飞行时间质谱仪，可在线性模式和反射电子模式下工作，分辨率分别为650和1350。使用倍频，三倍和四倍的Nd：YAG激光，其波长为266 ，355、553和1064 nm供选择。使用同轴观察系统将激光束聚焦到10或100 um的直径。通常获得亚皮摩尔水平的敏感性。

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来源
《First international symposium on bioanalytical chemistry》|1995年|10-11|共2页
会议地点 Xian(CN);Xian(CN)
作者
Shankai Zhao; Feng Zhong;
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作者单位

Instrumentation Analysis Research Centre Zhongshan University, Guangzhou, P. R. China;

Instrumentation Analysis Research Centre Zhongshan University, Guangzhou, P. R. China;

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原文格式 PDF
正文语种 eng
中图分类一般性问题;
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THE METHOD OF MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY (MALDI- MS) AND ITS APPLICATION IN BIOANALYSIS

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