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首页> 外文会议>First international symposium on bioanalytical chemistry >FLUORESENCE QUENCHING STUDYS ON XANTHINES WITH ALBUMIN
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FLUORESENCE QUENCHING STUDYS ON XANTHINES WITH ALBUMIN

机译：黄酮与白蛋白的荧光猝灭研究

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摘要

Serum albumin is the most abandent protein in blood plasm and serves as a depot protein and transport protein for numerous endogenous and exogenous compands. The interactions have been investigated widely. Caffeine and Theophylline are of particular interest for their clinical, pharmacological and biological proterties. It is well known that the binding of drugs with proteins has a great influence not only upon the distribution of the drugs in the body but also upon their patterns of metabolism and excretion. Futher, from the standpoint of drug efficacy, only that portion of a drug which is not bound with plasma proteins is generally bio-active. Thus, the study of the binding characteristics of medical drugs to protein is an important field.
机译：血清白蛋白是血浆中最缺乏的蛋白质，并且是许多内源性和外源性复合物的贮库蛋白和转运蛋白。相互作用已被广泛研究。咖啡因和茶碱因其临床，药理和生物学特性而特别受关注。众所周知，药物与蛋白质的结合不仅对药物在体内的分布有很大影响，而且对它们的代谢和排泄方式也有很大的影响。此外，从药物功效的观点来看，药物中仅不与血浆蛋白结合的那部分通常具有生物活性。因此，研究药物与蛋白质的结合特性是重要的领域。

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  • 来源
  • 会议地点 Xian(CN);Xian(CN)
  • 作者

    Z. Y. Huang; L. Xu; Z. H. Chen; Q. Yin;

  • 作者单位

    Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, China;

    Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, China;

    Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, China;

    Department of Chemistry, Wuhan University, Wuhan, Hubei 430072, China;

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  • 正文语种 eng
  • 中图分类 一般性问题;
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