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首页> 外文会议>Laser Florence 2017: Advances in Laser Medicine >Treatment of complicated gangrene using infrared photodynamic therapy
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Treatment of complicated gangrene using infrared photodynamic therapy

机译：红外光动力疗法治疗复杂性坏疽

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Background Antimicrobial photodynamic therapy (aPDT) is one of the treatment options of local infections. Conventional aPDT systems have physical limitations such as low light penetration and the need for long irradiation time to achieve the necessary light dose. With new forming specific complex of methylene blue dye molecules it is possible to reach efficient excitation processes at 810nm. At 810nm, there is increased light penetration depth in comparison to 670nm. This means that we are now able to excite the sensitizer in deeper areas and activate it transgingivally. Purpose Preserving teeth with complicated gangrene is a great challenge if root canal is obstructed. Lacking the possibility to perform the conventional mechanical cleaning of root canals. we have used infrared photodynamic therapy for elimination radicular bacterial infiltration Materials and methods We investigated 14 cases with complicated gangrene and totally or partially obstructed root canal. We deposited the sensitizer - Photolase Photolase GMBH Germany - in the pulp chamber and closed it for a week. This procedure was repeated three times. After the sensitizer penetrated we applied the light. We used G-Box 810 nm laser - Gigaa Laser China - at 0,8W/cm~2, 40s buccal and 40s oral side. Results 6 month later we performed follow-up CBCT. Out of 14 cases significant healing was detected in 10. In 4 cases no change was observable. Discussion and conclusion Infrared aPDT seems effective in eliminating bacterial infiltrations in deeper areas. It can be a minimal invasive method in the case of obstructed root canals.
机译：背景技术抗菌素光动力疗法（aPDT）是局部感染的治疗选择之一。常规的aPDT系统具有物理限制，例如光穿透率低以及需要很长的照射时间才能达到所需的光剂量。使用新形成的亚甲蓝染料分子的特定复合物，可以在810nm处达到有效的激发过程。与670nm相比，在810nm处增加了光穿透深度。这意味着我们现在能够在更深的区域激发敏化剂并通过齿龈激活它。目的如果根管受阻，保留具有复杂坏疽的牙齿是一个巨大的挑战。缺乏进行常规的根管机械清洁的可能性。我们已经使用红外光动力疗法消除了放射状细菌的浸润。材料和方法我们调查了14例复杂的坏疽和完全或部分阻塞根管的病例。我们将感光剂-德国Photolase Photolase GMBH存放在果肉室中，并关闭了一周。将该程序重复三遍。敏化剂渗透后，我们施加了光。我们使用G-Box 810 nm激光-Gigaa Laser China-在0.8W / cm〜2、40s颊侧和40s口腔侧使用。结果6个月后，我们进行了随访CBCT。在14例中，有10例被发现有明显的愈合。在4例中，没有观察到变化。讨论和结论红外aPDT似乎可以消除更深区域的细菌渗透。对于根管阻塞的情况，这可能是一种微创方法。

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