Biosensing platform with tapered optical microfibers: new results

机译：带有锥形光学微纤维的生物传感平台：新结果

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Our research demonstrates the design and fabrication of a biosensor based on the tapered optical fiber. The fiber is tapered biconically to a diameter of approximately 7 μm, which allows the evanescent field of propagating light to interact with molecules attached to the tapered surface. This sensing platform is capable of fast, continuous, specific, sensitive, and label-free molecular detection in the aqueous phase. Detection is demonstrated across multiple fibers, and the individual fibers are reusable. The system described previously has been modified for detection of volatile organic compounds. The fabrication of the modified design is also shown with preliminary results.

机译：我们的研究证明了基于锥形光纤的生物传感器的设计和制造。光纤呈双锥形渐缩到大约7μm的直径，这使传播的渐逝光与附着在渐缩表面上的分子相互作用。该传感平台能够在水相中进行快速，连续，特异性，灵敏且无标记的分子检测。可以在多根光纤上检测到，并且可以重复使用单个光纤。先前描述的系统已经过修改，可以检测挥发性有机化合物。修改后的设计的制作也显示了初步结果。

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来源
《Frontiers in biological detection: from nanosensors to systems VI》|2014年|893303.1-893303.7|共7页
会议地点 San Francisco CA(US)
作者
Branden J. King; Ighodalo Idehenre; Peter E. Powers; Joseph W. Haus; Karolyn M. Hansen;
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作者单位

Biology Department, University of Dayton;

Electro-Optics Program, University of Dayton;

Electro-Optics Program, University of Dayton,Physics Department, University of Dayton;

Electro-Optics Program, University of Dayton,Physics Department, University of Dayton;

Biology Department, University of Dayton;

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原文格式 PDF
正文语种 eng
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关键词
biosensor; biosensing; taper; fiber; antibody; antigen;

机译：生物传感器生物传感锥度纤维;抗体;抗原;

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专利

1. Novel Microfiber Sensor and Its Biosensing Application for Detection of hCG Based on a Singlemode-Tapered Hollow Core-Singlemode Fiber Structure [J] . Chen Ling, Liu Bin, Liu Juan, IEEE sensors journal . 2020,第16期

机译：基于单倍细芯芯单晶纤维结构的新型微纤维传感器及其用于检测HCG的生物传感器
2. Generating Localized Plasmonic Fields on an Integrated Photonic Platform using Tapered Couplers for Biosensing Applications [J] . Gurpreet Singh, Renzhe Bi, U. S. Dinish, Scientific reports. . 2017,第1期

机译：使用锥形耦合器在集成光子平台上产生局部等离子体场，用于生物传感器应用
3. Characterization of scattering losses in tapered optical fibers perturbed by a microfiber tip [J] . Zhang Pengfei, Wang Xin, Song Lijun, Journal of the Optical Society of America, B. Optical Physics . 2020,第5期

机译：微纤维尖端斑块光纤中散射损耗的特征
4. A side-grooved optical microfiber taper with polymer coating for highly sensitive temperature sensing [C] . Jianjun Zhou, Donglai Guo, Minghong Yang IEEE Sensors . 2019

机译：具有高敏感温度传感的聚合物涂层的侧槽光学微纤维锥度
5. Studies of tapered single-mode optical fiber devices for hybridization-based biosensing and other applications. [D] . Hodzic, Vildana. 2002

机译：用于基于杂交的生物传感和其他应用的锥形单模光纤设备的研究。
6. Generating Localized Plasmonic Fields on an Integrated Photonic Platform using Tapered Couplers for Biosensing Applications [O] . Gurpreet Singh, Renzhe Bi, U. S. Dinish, -1

机译：使用锥形耦合器在生物传感应用中的集成光子平台上生成局部等离子场
7. Fluorescence excitation on tapered polymer optical fibers through microfiber evanescent field [O] . Rodriguez Schwendtner E., Navarrete Fernández María Cruz, Esteban Óscar, 2015

机译：通过微纤维渐逝场对锥形聚合物光纤进行荧光激发

Biosensing platform with tapered optical microfibers: new results

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