• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>Frontiers in biological detection: from nanosensors to systems VI >Highly sensitive integrated optical biosensors
【24h】

Highly sensitive integrated optical biosensors

机译：高灵敏度集成光学生物传感器

获取原文
获取原文并翻译 | 示例
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Optical sensor systems for biological and medical applications have been widely developed in order to satisfy the current requirements such as a miniaturization, cost reduction, label-free detection and fast response. Here, we demonstrate a highly sensitive optical sensor based on two cascaded microring resonators (MRRs) exploiting the Vernier effect. The architecture consists of a filter MRR connected to a sensor MRR via a common waveguide. The external medium of the filter MRR is isolated with a top cladding layer, while the sensor MRR interacts with the analyte sample via an opening. The sensor chip, that includes an array of five cascaded MRRs, was designed and fabricated on a silicon nitride platform. A first test has been performed with sodium chloride (NaCl) concentrations in deionized (DI) water providing a sensitivity of 1.03 nm/% (6317 nm/RIU). A limit of detection of 3.16 × 10~(-6) RIU was demonstrated for the current sensor, respectively. Several concentrations of isopropanol in ethanol ranging from 0% to 10% were also investigated. These preliminary measurements show a sensitivity as high as 0.95 nm/% at ～1535 nm compared to 0.02 nm/% from a single sensor MRR. For a moderated alignment between the chip and cleaved optical fibers, tapered grating couplers are included at the ends of waveguides. Hence, by combining the Vernier effect and the silicon nitride material, cascaded MRRs will be a powerful optical configuration for biosensing applications in a wide operating wavelength range.
机译：为了满足诸如小型化，降低成本，无标签检测和快速响应的当前要求，已经广泛开发了用于生物和医学应用的光学传感器系统。在这里，我们演示了一种基于高精度的光学传感器，该传感器基于两个利用Vernier效应的级联微环谐振器（MRR）。该架构包括一个滤波器MRR，该滤波器MRR通过公共波导连接到传感器MRR。过滤器MRR的外部介质被上覆层隔离，而传感器MRR通过开口与分析物样品相互作用。包含五个级联MRR的阵列的传感器芯片是在氮化硅平台上设计和制造的。已经用去离子（DI）水中的氯化钠（NaCl）浓度进行了第一项测试，提供了1.03 nm /％（6317 nm / RIU）的灵敏度。电流传感器的检出限分别为3.16×10〜（-6）RIU。还研究了乙醇中异丙醇的几种浓度，范围从0％到10％。这些初步测量显示，在〜1535 nm处灵敏度高达0.95 nm /％，而单个传感器MRR的灵敏度为0.02 nm /％。为了使芯片和劈开的光纤之间的对准适中，在波导的端部包括锥形光栅耦合器。因此，通过将Vernier效应和氮化硅材料相结合，级联MRR将成为在宽工作波长范围内用于生物传感应用的强大光学配置。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号