SERS spectroscopy, electrical recording and intracellular injection in neuronal networks with 3D plasmonic nanoantennas

机译：具有3D等离子体纳米天线的神经网络中的SERS光谱，电记录和细胞内注射

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We developed a platform based on 3D plasmonic nanoantennas able to perform different functions with applications in the biological research area. In particular it will be shown how the peculiar geometry of the system plays a fundamental role, leading to a tight interaction with the cellular membrane. Such configuration allows on one side the investigation of extracellular features through enhanced vibrational spectroscopy and electrical recording, and on the other the possibility of intracellular injection by optoporation. In this regard it will be demonstrated how the characteristics of the laser pulse used for exciting the antenna establish the kind of involved phenomena. A dependence of these properties on the metal coating the antenna will be also shown.

机译：我们开发了基于3D等离子体纳米天线的平台，该平台能够在生物学研究领域中的应用中执行不同的功能。特别是将显示系统的特殊几何形状如何起基本作用，从而导致与细胞膜的紧密相互作用。这种配置一方面允许通过增强的振动光谱和电记录来研究细胞外特征，另一方面允许通过对位作用进行细胞内注射。在这方面，将证明用于激励天线的激光脉冲的特性如何建立所涉及的现象。这些特性对天线金属涂层的依赖性也将显示出来。

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来源
《Frontiers in ultrafast optics: biomedical, scientific, and industrial applications XVI》|2016年|974002.1-974002.7|共7页
会议地点 San Francisco CA(US)
作者
Valeria Caprettini; Gabriele C. Messina; Michele Dipalo; Rosanna La Rocca; Andrea Cerea; Francesco De Angelis;
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作者单位

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genova, Italy;

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原文格式 PDF
正文语种 eng
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关键词
Plasmonic; Optoporation; Hot-electrons;

机译：血浆对立;热电子;

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专利

1. A micro-optrode for simultaneous extracellular electrical and intracellular optical recording from neurons in an intact oscillatory neuronal network. [J] . Bradley PM, Murphy D, Kasparov S, Journal of Neuroscience Methods . 2008,第2期

机译：一种微电极，用于同时从完整的振荡神经元网络中的神经元进行细胞外电和细胞内光学记录。
2. Intracellular and Extracellular Recording of Spontaneous Action Potentials in Mammalian Neurons and Cardiac Cells with 3D Plasmonic Nanoelectrodes [J] . Dipalo Michele, Amin Hayder, Lovato Laura, Nano letters . 2017,第6期

机译：哺乳动物神经元和3D等级纳米电极的哺乳动物神经元和心脏细胞的细胞外和细胞外记录
3. Intracellular and Extracellular Recording of Spontaneous Action Potentials in Mammalian Neurons and Cardiac Cells with 3D Plasmonic Nanoelectrodes [J] . Michele Dipalo, Hayder Amin, Laura Lovato, JPC Bulletin on Iron & Steel . 2017,第6期

机译：哺乳动物神经元和三维等离子体纳米电池中的自发动作电位的细胞外和细胞外记录
4. SERS spectroscopy, electrical recording and intracellular injection in neuronal networks with 3D plasmonic nanoantennas. [C] . Valeria Caprettini, Gabriele C. Messina, Michele Dipalo, SPIE Conference on Frontiers in Ultrafast Optics: Biomedical, Scientific, and Industrial Applications . 2016

机译：三维等离子体纳米环纳米神经网络中的SERS光谱，电气记录和细胞内注射。
5. Microneedle devices for intracellular neuronal recording and high throughput cellular interrogation. [D] . Govindarajan, Anupama V. 2009

机译：用于细胞内神经元记录和高通量细胞询问的微针设备。
6. Second harmonic generation spectroscopy on hybrid plasmonic/dielectric nanoantennas [O] . Heiko Linnenbank, Yevgen Grynko, Jens Förstner, 2016

机译：混合等离子体/介电纳米天线的二次谐波产生光谱
7. Electrical tuning of exciton-plasmon polariton coupling in monolayer MoS2 integrated with plasmonic nanoantenna lattice [O] . Lee, Bumsu, Liu, Wenjing, Naylor, Carl H., 2016

机译：单层激子 - 等离子体激元耦合的电学调谐 mos2与等离子体纳米天线晶格结合

SERS spectroscopy, electrical recording and intracellular injection in neuronal networks with 3D plasmonic nanoantennas

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