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首页> 外文会议>Frontiers in ultrafast optics: biomedical, scientific, and industrial applications XVII >Ultrafast pulsed Bessel beams for enhanced laser ablation of bone tissue for applications in LASSOS
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Ultrafast pulsed Bessel beams for enhanced laser ablation of bone tissue for applications in LASSOS

机译：超快脉冲贝塞尔光束，用于在LASSOS中应用的增强的骨组织激光消融

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摘要

Using a femtosecond pulsed laser system (pulse width = 100fs, repetition rate = 1 kHz, λ=800nm), a zero-order Bessel beam was generated using a LCOS-Spatial light modulator (LCOS-SLM) with an effective cone angle of 4.56°. Ablation threshold studies of fresh bovine and ovine load bearing cortical bone was identified using the method of least damage and found to be identical at φ_(th) = 0.15 ± 0.03 J cm~(-2), irrespective of the target species. The ablation threshold is significantly reduced compared to the ablation threshold determined for Gaussian beams in bovine and ovine cortical bone (Load Bearing: φ_(th) = 0.91 ± 0.03 J cm~(-2), Skull: φ_(th) = 1.19 ± 0.06 J cm~(-2)). Incubation effects were investigated and the incubation coefficient was determined to be ζ = 0.93 ± 0.06, indicating no incubation effects are present. The relationship between tissue removal and the number of pulses applied was explored. By altering the translation rate of the sample under the Bessel region of the incident laser, the number of pulses applied at each point along the linear ablation features was varied. Cross sections of ablation features were measured using scanning electron microscopy (SEM) and maximum depths of the ablation features measured. The ablation rate of bovine and ovine cortical was found to be 2.69 - 13.21 ± 0.05 μm pulse~(-1) and 2.49 - 12.79 ± 0.03 μm pulse~(-1) respectively for fluence values ranging from 2.5 - 25.0 Jcm~(-2), significantly higher than those of Gaussian beams. Structural analysis of the ablation features using SEM and optical microscopy showed no signs of heat affected zone (HAZ) in the form of thermal shockwave cracking, molten debris deposition or charring of the tissue.
机译：使用飞秒脉冲激光系统（脉冲宽度= 100fs，重复频率= 1 kHz，λ= 800nm），使用有效锥角为4.56的LCOS空间光调制器（LCOS-SLM）生成零级贝塞尔光束。 °。使用损伤最小的方法确定了新鲜牛和绵羊负重皮质骨的消融阈值研究，发现在φ_（th）= 0.15±0.03 J cm〜（-2）时相同，与目标物种无关。与为牛和绵羊皮质骨中的高斯光束确定的消融阈值相比，消融阈值显着降低（承载：φ_（th）= 0.91±0.03 J cm〜（-2），头骨：φ_（th）= 1.19± 0.06 J cm〜（-2））。研究了孵化效果，孵化系数确定为ζ= 0.93±0.06，表明不存在孵化效果。探索了组织去除与施加的脉冲数之间的关系。通过改变样品在入射激光的贝塞尔区域下的平移速率，沿线性烧蚀特征在每个点施加的脉冲数可以改变。使用扫描电子显微镜（SEM）测量消融特征的横截面，并测量消融特征的最大深度。当注量范围为2.5-25.0 Jcm〜（-）时，牛和绵羊皮层的消融率分别为2.69-13.21±0.05μmPulse〜（-1）和2.49-12.79±0.03μmpulse〜（-1）。 2），明显高于高斯光束。使用SEM和光学显微镜对消融特征进行结构分析，未发现热冲击波破裂，熔融碎片沉积或组织炭化形式的热影响区（HAZ）迹象。

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  • 会议地点 San Francisco(US)
  • 作者

    Simon A. Ashforth; Reece N. Oosterbeek; M. Cather Simpson;

  • 作者单位

    Department of Physics, University of Auckland, 23 Symonds Street, Auckland, New Zealand ,Photon Factory, Macdiarmid Institute for Advanced Materials and Nanotechnology Dodd-Walls Centre for Photonics and Quantum Technologies;

    School of Chemical Sciences, University of Auckland, 23 Symonds Street, New Zealand ,Photon Factory, Macdiarmid Institute for Advanced Materials and Nanotechnology Dodd-Walls Centre for Photonics and Quantum Technologies;

    Department of Physics, University of Auckland, 23 Symonds Street, Auckland, New Zealand ,School of Chemical Sciences, University of Auckland, 23 Symonds Street, New Zealand ,Photon Factory, Macdiarmid Institute for Advanced Materials and Nanotechnology Dodd-Walls Centre for Photonics and Quantum Technologies;

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  • 正文语种 eng
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  • 关键词

    Bessel beam; LASSOS; Laser ablation; Bone laser machining; femtosecond laser ablation; spatial light modulator;

    机译：贝塞尔光束拉索斯;激光烧蚀；骨激光加工；飞秒激光消融；空间光调制器;

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