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首页> 外文会议>Genetically Engineered and Optical Probes for Biomedical Applications IV; Progress in Biomedical Optics and Imaging; vol.8 no.26; Proceedings of SPIE-The International Society for Optical Engineering; vol.6449 >Concentration dependent absorption and scattering characteristics of gold nanoparticles embedded in liquid phantoms
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Concentration dependent absorption and scattering characteristics of gold nanoparticles embedded in liquid phantoms

机译：液态幻影中嵌入的金纳米粒子的浓度依赖性吸收和散射特性

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摘要

For biomedical applications, various optical techniques have been explored, all of which are inherently subject to the limited penetration depth of observation. Nanoparticles have thus been introduced as a potential agent to overcome the limit and to reveal more information on biomedical samples. Optical properties of nanoparticles in a turbid medium, however, have remained difficult to measure precisely. In this paper, we investigate the scattering and absorbing properties of gold nanoparticles of varying diameter and different concentration in absorbing liquid phantoms of silica colloid, based on diffuse photometry. Diffuse reflectance patterns have been collected for each phantom with nanoparticles of different size and concentrations relative to base media. The results imply that particle concentration and size perturbs the medium properties, and the effect is dependent on the scattering properties of the particle. For the case where the particle size stays within a range, the scattering property is dominated by the concentration.
机译：对于生物医学应用，已经探索了各种光学技术，所有这些技术固有地都受到观察深度的限制。因此，已引入纳米颗粒作为潜在的试剂，以克服该限制并揭示生物医学样品的更多信息。然而，在浑浊的介质中纳米颗粒的光学性质仍然难以精确测量。在本文中，我们基于漫射光度法研究了不同直径和不同浓度的金纳米粒子在二氧化硅胶体吸收液体模型中的散射和吸收特性。相对于基础介质，已经为每个体模收集了具有不同大小和浓度的纳米粒子的漫反射模式。结果表明，颗粒浓度和尺寸会扰乱介质的性能，其效果取决于颗粒的散射性能。对于粒径保持在一定范围内的情况，散射特性由浓度决定。

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