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首页> 外文会议>Molecular-Guided Surgery: Molecules, Devices, and Applications IV >Optimization of the incident wavelength for Mueller matrix imaging of cervical collagen
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Optimization of the incident wavelength for Mueller matrix imaging of cervical collagen

机译：宫颈胶原Mueller矩阵成像的入射波长的优化

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摘要

Mueller matrix polarimetry (MMP) can be utilized to determine optical anisotropy in birefringent materials. Many factors must be optimized to improve the quality of information collected from MMP of biological samples. As part of a study on pre-term birth (PTB) that relied on measurement of the orientation and distribution of collagen in the cervix, an optimal wavelength for MMP to allow more accurate characterization of collagen in cervical tissue was sought. To this end, we developed a multispectral Mueller matrix polarimeter and conducted experiments on ex-vivo porcine cervix samples preserved in paraffin. The Mueller matrices obtained with this system were decomposed to generate orientation and retardation images. Initial findings indicate that wavelengths below 560 nm offer a more accurate characterization of collagen anisotropy in the porcine cervix.
机译：穆勒矩阵旋光法（MMP）可用于确定双折射材料中的光学各向异性。必须优化许多因素以提高从生物样品的MMP收集的信息的质量。作为一项依靠测量子宫颈中胶原蛋白的方向和分布的早产研究的一部分，人们寻求一种MMP的最佳波长，以更准确地表征宫颈组织中的胶原蛋白。为此，我们开发了多光谱Mueller矩阵旋光仪，并对保存在石蜡中的离体猪宫颈样品进行了实验。用该系统获得的穆勒矩阵被分解以产生取向和延迟图像。初步发现表明，低于560 nm的波长可更准确地表征猪宫颈中的胶原各向异性。

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