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首页> 外文会议>Health Monitoring and Smart Nondestructive Evaluation of Structural and Biological Systems V >Anemia Detection utilizing diffuse reflectance spectra from the palpebral conjunctiva and tunable liquid crystal filter technology
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Anemia Detection utilizing diffuse reflectance spectra from the palpebral conjunctiva and tunable liquid crystal filter technology

机译：利用来自睑结膜的漫反射光谱和可调谐液晶滤光片技术进行贫血检测

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摘要

Anemia is a serious worldwide disorder affecting 2 billion people globally. While the only clinically accepted method of diagnosis remains an invasive blood draw and laboratory analysis, numerous attempts have been made to measure total blood hemoglobin noninvasively. Although the palpebral conjunctiva can be used as a poor qualitative indicator of anemia, a quantitative analysis of the conjunctiva using visible diffuse reflectance spectroscopy can provide an accurate and easy method of noninvasive measurement. Preliminary studies using a traditional grating based spectrometer have shown this method of analysis to be effective and accurate at diagnosing anemia and are presented here. An alternative device to collect diffuse reflectance spectroscopy based on tunable liquid crystal technology that is comparatively inexpensive and compact is also presented. Deformed helix ferroelectric liquid crystals (DHFLC) can be tuned fully across the visible spectrum and have a narrow bandwidth of reflection. A handheld microspectrometer facilitates this technique becoming a clinically viable method of analysis and enables total hemoglobin to be measured quickly, and without the need of a blood draw. The rapidity of this test can make total hemoglobin measurement a new vital sign, increasingly important because of the concurrent appearance of anemia with numerous other disorders.
机译：贫血是一种严重的全球性疾病，影响全球20亿人。尽管唯一的临床上公认的诊断方法仍然是侵入性抽血和实验室分析，但已进行了许多尝试来非侵入性地测量全血血红蛋白。尽管睑结膜可作为贫血的不良定性指标，但使用可见漫反射光谱法对结膜进行定量分析可提供一种准确，简便的无创测量方法。使用传统的基于光栅的光谱仪进行的初步研究表明，这种分析方法可有效且准确地诊断贫血，并在此处介绍。还提出了一种基于可调谐液晶技术的收集漫反射光谱的替代装置，该装置相对便宜且紧凑。变形的螺旋铁电液晶（DHFLC）可以在可见光谱范围内完全调谐，并且反射带宽窄。手持式显微光谱仪有助于该技术成为临床上可行的分析方法，并能够快速测量总血红蛋白，而无需抽血。这项测试的快速性可以使总血红蛋白的测量成为一个新的生命体征，由于贫血与许多其他疾病同时出现，这一点变得越来越重要。

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