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首页> 外文会议>Image Processing pt.3; Progress in Biomedical Optics and Imaging; vol.8,no.31; Proceedings of SPIE-The International Society for Optical Engineering; vol.6512 pt.3 >Orientation-Weighted, Local Minkowski Functionals in 3D for Quantitative Assessment of Trabecular Bone Structure in the Hip
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Orientation-Weighted, Local Minkowski Functionals in 3D for Quantitative Assessment of Trabecular Bone Structure in the Hip

机译：3D方向加权局部Minkowski功能可对髋骨小梁骨结构进行定量评估

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摘要

Fragility fractures or pathologic fractures of the hip, I.e. fractures with no apparent trauma, represent the worst complication in osteoporosis with a mortality close to 25% during the first post-traumatic year. Over 90% of hip fractures result from falls from standing height. A substantial number of femoral fractures are initiated in the femoral neck or the trochanteric regions which contain an internal architecture of trabeculae that are functionally highly specialized to withstand the complex pattern of external and internal forces associated with human gait. Prediction of the mechanical strength of bone tissue can be achieved by dedicated texture analysis of data obtained by high resolution imaging modalities, e.g. computed tomography (CT) or magnetic resonance tomography (MRI). Since in the case of the proximal femur, the connectivity, regional distribution and - most of all - the preferred orientation of individual trabeculae change considerably within narrow spatial limits, it seems most reasonable to evaluate the femoral bone structure on an orientation-weighted, local scale. In past studies, we could demonstrate the advantages of topological analysis of bone structure using the MinkowskirnFunctionals in 3D on a global and on a local scale. The current study was designed to test the hypothesis that the prediction of the mechanical competence of the proximalrnfemur by a new algorithm considering orientational changes of topological properties in the trabecular architecture isrnfeasible and better suited than conventional methods based on the measurement of the mineral density of bone tissuern(BMD).
机译：髋部易碎性骨折或病理性骨折没有明显外伤的骨折是骨质疏松症中最严重的并发症，在创伤后的第一年死亡率接近25％。超过90％的髋部骨折是由于站立时跌落造成的。大量股骨骨折始于股骨颈或股骨转子区，这些股骨包含小梁的内部结构，这些结构在功能上高度专门化，可以承受与人的步态相关的外力和内力的复杂模式。骨组织机械强度的预测可以通过对通过高分辨率成像模态（例如，超声成像）获得的数据进行专门的纹理分析来实现。计算机断层扫描（CT）或磁共振断层扫描（MRI）。由于在股骨近端的情况下，单个小梁的连接性，区域分布以及最重要的是首选的小梁方向在狭窄的空间范围内发生了很大的变化，因此，以方向加权的局部方法评估股骨的结构似乎是最合理的。规模。在过去的研究中，我们可以在全球和局部范围内使用MinkowskirnFunctional在3D中展示骨骼结构拓扑分析的优势。当前的研究旨在验证以下假设：考虑到骨小梁结构中拓扑特性的方向变化的新算法，考虑到骨小梁结构中拓扑特性的方向变化，用新算法预测近端股骨的机械能力是可行的，并且比传统方法更适合组织（BMD）。

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