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Threshold effects in assembling a cell on a young planet

机译:在年轻星球上组装细胞的阈值效应

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Molecules in the young Earth's oceans underwent a finite number C of collisions during the time interval which elapsed between Earth's formation and the emergence of life. The finiteness of C sets an upper limit G on the number of constituent molecules which could have been randomly assembled into a genetic molecule from a reservoir of the relevant constituent molecules for use in the first cell. A viable cell requires a certain minimum number of genes in order to be functional: this means that the genetic material must include a minimum number M of the constituent molecules which encode for information. The question we address here is: is it mathematically possible for G to take on values which are at least as large as M? The answer is Yes, provided that we allow for the fact that there is a large amount of flexibility ("non-specificity") in the operation of biological molecules. When this flexibility is allowed for, we find that G can be comparable to M provided that the mass of constituent molecules which were available in the pre-biotic Earth exceeded a certain threshold. Our estimates indicate that a mass on the order of a few tons would satisfy the threshold.
机译:在地球形成与生命出现之间的时间间隔内,年轻的地球海洋中的分子经历了有限数量的碰撞。 C的有限度对可能已经从用于第一细胞的相关组成分子的储库中随机组装成遗传分子的组成分子的数目设置了上限G。活细胞需要一定数量的最小基因才能发挥功能:这意味着遗传材料必须包括最少M个编码信息的组成分子。我们在这里解决的问题是:在数学上G是否可以取至少等于M的值?答案是肯定的,只要我们考虑到生物分子操作中存在大量灵活性(“非特异性”)这一事实。当允许这种灵活性时,我们发现只要益生元地球中可用的组成分子的质量超过某个阈值,G就可以与M相当。我们的估计表明,大约几吨的质量将满足阈值。

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