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首页> 外文会议>International Manufacturing Science and Engineering Conference >SURFACE MODIFICATIONS OF TITANIUM WITH COVALENTLY-BONDED SILVER NANOPARTICLES FOR ANTIMICROBIAL APPLICATIONS
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SURFACE MODIFICATIONS OF TITANIUM WITH COVALENTLY-BONDED SILVER NANOPARTICLES FOR ANTIMICROBIAL APPLICATIONS

机译：共价键合的银纳米粒子对钛的表面改性

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Formation of biofilm on implant surface is one of the major causes for port-operative infection. Incorporation of antimicrobial silver nanoparticles (AgNPs) on implant surface has been studied as an effective remedy in recent decades. This paper presents a novel AgNPs-titanium composite foil manufactured through covalent attachment of AgNPs for biofilm control. This composite foil was fabricated by a series of chemical reactions including thiol-derivatization and formation of Ag-S covalent bonds. The film structure and properties were characterized through scanning electron microscopy (SEM), Energy dispersive X-ray Spectroscopy (EDS) and surface profiling. The antimicrobial performance was examined against gram positive bacterial strain Staphylococcus aureus. Results indicate that the prepared composite foil effectively reduced bacterial attachment in short term exposure and possess high stability against the release of nanoparticles. This novel antimicrobial composite material has a great potential to be used in the future biomedical instrumentation.
机译：植入物表面生物膜的形成是港口手术感染的主要原因之一。近几十年来，已经研究了将抗菌性银纳米颗粒（AgNPs）植入植入物表面的有效方法。本文介绍了一种新型的AgNPs-钛复合箔，它是通过AgNPs的共价结合制成的，用于生物膜的控制。该复合箔是通过一系列化学反应制备的，包括硫醇衍生化和形成Ag-S共价键。膜的结构和性能通过扫描电子显微镜（SEM），能量色散X射线光谱（EDS）和表面轮廓进行表征。检查了对革兰氏阳性细菌金黄色葡萄球菌的抗菌性能。结果表明，所制备的复合箔在短期暴露下能有效减少细菌附着，并具有抵抗纳米颗粒释放的高稳定性。这种新型的抗菌复合材料具有巨大的潜力，可以在未来的生物医学仪器中使用。

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