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首页> 外文会议>International Workshop on Breast Imaging >Preliminary Experiences of DBT (digital breast tomosynthesis) and Hybrid 18F-FDG-PET/MR (PETMR) for Neoadjuvant Chemotherapy (NAC) Cases in Breast Cancer
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Preliminary Experiences of DBT (digital breast tomosynthesis) and Hybrid 18F-FDG-PET/MR (PETMR) for Neoadjuvant Chemotherapy (NAC) Cases in Breast Cancer

机译：DBT（数字乳腺断层合成）和混合18F-FDG-PET / MR（PETMR）在乳腺癌新辅助化疗（NAC）病例中的初步经验

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Twenty-six patients with 27 invasive breast cancers were enrolled and MMG+DBT, US, and PETMR were obtained before and after NAC. The clinical response to chemotherapy was classified into the following categories, based on the RECIST and pathological response was classified in accordance with JBCS. Among Grade 3 (n=7), MMG+DBT demonstrated as CR by 71.4% and as PR by 28.6%. Among PR lesions, estimated pathological response was Grade 2 (n=2). PETMR demonstrated as PR by 57.1% and as CR by 42.9%. Among PR lesions, estimated pathological response was Grade 2 (n=4). FDG uptake was positive before and negative after NAC with all primary lesions. Among Grades 1b-2 (n=15), MMG +DBT demonstrated as PR by 76.3% (n=11) and four as CR by 26.7% (n=4). Among PR lesions, estimated pathological response were Grade 1b (n=5) and Grade 2 (n=6). PETMR demonstrated as PR by 80.0% and as CR by 20.0%. Among PR lesions, estimated pathological response were Grade 1b (n=3) and Grade 2 (n=9). After NAC, FDG uptake was positive in primary lesions by 20.0% (n=3). Among Grade 0-1a (n=5), MMG+DBT demonstrated as SD by 60.0 % and as PR by 40.0%. Among PR lesions, estimated pathological response were Grade lb (n=1) and Grade 2 (n=1). PETMR demonstrated as SD by 40.0 % and as PR by 60.0%. Among PR lesions, estimated pathological response were Grade lb (n=2) and Grade 2 (n=1). After NAC, FDG uptake was positive in primary lesions by 80.0% (n=4).
机译：在NAC之前和之后，纳入了26例27种浸润性乳腺癌患者，并获得了MMG + DBT，US和PETMR。根据RECIST，对化学疗法的临床反应分为以下几类，并根据JBCS对病理反应进行了分类。在3级（n = 7）中，MMG + DBT的CR率为71.4％，PR的率为28.6％。在PR病变中，估计的病理反应为2级（n = 2）。 PETMR显示PR为57.1％，CR为42.9％。在PR病变中，估计的病理反应为2级（n = 4）。在所有主要病变的NAC之前，FDG摄取均为阳性，之后为阴性。在1b-2年级（n = 15）中，MMG + DBT的PR表现为76.3％（n = 11），四个CR表现为26.7％（n = 4）。在PR病变中，估计的病理反应为1b级（n = 5）和2级（n = 6）。 PETMR显示PR为80.0％，CR为20.0％。在PR病变中，估计的病理反应为1b级（n = 3）和2级（n = 9）。 NAC后，原发灶中FDG摄取阳性20.0％（n = 3）。在0-1a级（n = 5）中，MMG + DBT的SD和PR分别为60.0％和40.0％。在PR病变中，估计的病理反应为1b级（n = 1）和2级（n = 1）。 PETMR的SD表现为40.0％，PR表现为60.0％。在PR病变中，估计的病理反应为1b级（n = 2）和2级（n = 1）。 NAC后，原发灶的FDG摄取阳性率为80.0％（n = 4）。

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