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CFD Simulation of the Portal Vein Blood Flow

机译：门静脉血流的CFD模拟

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A precise quantification of the blood flow in vessels under normal or abnormal conditions could constitute a strong basis for diagnosis, prediction or evolution estimation of blood vessels or associated organ diseases. Many fundamental issues of the blood flow are still not fully understood or entirely translated into mathematical formulations. Therefore, the computational modeling of the blood flow based on from medical imaging data is still a challenging task. The phenomena associated with pressure and viscous forces fields generate complex interactions which strongly affect the blood flow patterns. Description and integration of such phenomena in mathematical models by means of computer simulation provide critical information about hemodynamics in blood vessels. Computational Fluid Dynamics (CFD) techniques assure a complete description of the blood vessels behavior by allowing fluid-structure interaction data inclusion in constructed models. This kind of data cannot be extracted by direct in vivo or in vitro measurements. Moreover, simulation of the blood flow using CFD constitutes a noninvasive technique capable to provide comprehensive insights of the overall phenomena taking place at the most intimate level inside the sanguine vessels. The research is focused on hemodynamic investigation of a 3D portal vein main branches Magnetic Resonance Imaging (MRI) based reconstruction using CFD techniques. The simulation results are validated by comparison with in vivo Eco-Doppler measurements. The study is conducted for the development of software assistance solutions for patients therapy by providing useful information regarding the hemodynamic characteristics and dynamics associated with portal vein hypertension evolution.
机译：在正常或异常条件下对血管中血流的精确定量可为诊断血管疾病或相关器官疾病的诊断，预测或进化估计奠定坚实的基础。血流的许多基本问题仍未完全理解或完全转化为数学公式。因此，基于医学成像数据的血流计算建模仍然是一项艰巨的任务。与压力和粘性力场相关的现象会产生复杂的相互作用，从而强烈影响血流模式。通过计算机仿真在数学模型中对此类现象的描述和整合可提供有关血管内血液动力学的重要信息。计算流体动力学（CFD）技术通过允许在构造模型中包含流体-结构相互作用数据来确保对血管行为的完整描述。无法通过直接体内或体外测量来提取此类数据。此外，使用CFD对血流进行模拟构成了一种非侵入性技术，能够对在血缘血管内部最紧密的水平上发生的整体现象提供全面的见解。该研究专注于使用CFD技术对基于3D门静脉主分支的磁共振成像（MRI）重建的血液动力学研究。通过与体内生态多普勒测量结果进行比较来验证仿真结果。通过提供有关与门静脉高压演变相关的血液动力学特征和动力学的有用信息，进行了这项研究，以开发用于患者治疗的软件辅助解决方案。

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