Deducing Interactions in Partially Unspecified Biological Systems

机译：推论部分未指定的生物系统中的相互作用

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We show how a symbolic approach to the semantics of process algebras can be fruitfully applied to the modeling and analysis of partially unspecified biological systems, i.e., systems whose components are not fully known, cannot be described entirely, or whose functioning is not completely understood. This adds a novel deductive perspective to the use of process algebras within systems biology: the investigation of the behavioural or structural properties that unspecified components must satisfy to interact within the system. These can be computationally inferred, extending the effectiveness of the in silico experiments. The use of the approach is illustrated by means of case studies.

机译：我们展示了如何将过程代数语义的符号方法有效地应用于部分未指定的生物系统的建模和分析，即其组件尚不完全了解，无法完全描述或无法完全理解其功能的系统。这为系统生物学中过程代数的使用增加了新颖的演绎观点：未指定组件必须满足的行为或结构特性才能在系统内进行交互。这些可以通过计算得出，从而扩展了计算机模拟实验的有效性。通过案例研究说明了该方法的使用。

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来源
《International Conference on Algebraic Biology(AB 2007); 20070702-04; Castle of Hagenberg(AT)》|2007年|P.262-276|共15页
会议地点 Castle of Hagenberg(AT)
作者
Paolo Baldan; Andrea Bracciali; Linda Brodo; Roberto Bruni;
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作者单位

Dipartimento di Matematica Pura e Applicata, Universita di Padova, Italia;

Dipartimento di Informatica, Universita di Pisa, Italia;

Dipartimento di Scienze dei Linguaggi, Universita di Sassari, Italia;

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原文格式 PDF
正文语种 eng
中图分类代数、数论、组合理论;生物工程学（生物技术）;
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机译：推论部分未指定的生物系统中的相互作用

Deducing Interactions in Partially Unspecified Biological Systems

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