INTERACTION BETWEEN FLUID AND SOLID IN EXTRACELLULAR MATRIX

机译：胞外基质中流体与固体之间的相互作用

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To gain insight into the interaction between the extracellular fluid and the matrix, we applied the poroelastic theory and modelled the extracellular matrix as a deformable porous medium. We investigated effects of properties of the matrix, boundary conditions and water permeability at the surface of the matrix on the deformation and fluid movement in the matrix. Particular attention was given to the relative velocity of the extracellular fluid to the solid matrix under dynamic stimulations. The model provided spatial distributions as well as their temporal variations of pressure, solid deformation and fluid velocity. It can be used to interpret certain experiments and provide insight into the mechanical environment and flow conditions within the extracellular matrix.

机译：为了深入了解细胞外液与基质之间的相互作用，我们应用了多孔弹性理论，并将细胞外基质建模为可变形的多孔介质。我们研究了基质的性质，边界条件和基质表面的水渗透性对基质中的变形和流体运动的影响。特别注意在动态刺激下细胞外液与固体基质的相对速度。该模型提供了压力，固体变形和流体速度的空间分布及其时间变化。它可用于解释某些实验并提供对细胞外基质内机械环境和流动条件的了解。

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来源
《International Conference on Fluid Mechanics; 20040720-30; Dalian(CN)》|2004年|P.679-682|共4页
会议地点 Dalian(CN)
作者
Z Y. Li; Y. L. Lu; K. H. Parker; D. L. Bader; W. Wang;
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作者单位

Medical Engineering Division, Queen Mary, University of London, London E1 4NS, UK;

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会议组织
原文格式 PDF
正文语种 eng
中图分类流体力学;
关键词
poroelastic theory; extracellular matrix; tissue deformation and interstitial flow;

机译：多孔弹性理论；细胞外基质；组织变形和间质流;

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2. Effects of freezing-induced cell-fluid-matrix interactions on the cells and extracellular matrix of engineered tissues. [J] . Teo KY, DeHoyos TO, Dutton JC, Biomaterials . 2011,第23期

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机译：组合细胞外基质平台识别与转移相关的细胞 - 细胞外基质相互作用

INTERACTION BETWEEN FLUID AND SOLID IN EXTRACELLULAR MATRIX

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