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首页> 外文会议>International Federation of Automatic Control(IFAC) Symposium on Modelling and Control in Biomedical Systems; 20060920-22; Reims(FR) >REDUCED MODEL FOR FORCED EXPIRATION AND ANALYSIS OF ITS SENSITIVITY
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REDUCED MODEL FOR FORCED EXPIRATION AND ANALYSIS OF ITS SENSITIVITY

机译：精简的精简模型及其敏感性分析

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摘要

Pathological changes in the lung modify the shape of the flow-volume curve registered during forced expiration. Computational models allowing simulation of the test results are too complex for the estimation of their parameters. In this study a complex model was reduced by introduction of the functions scaling airway properties. Influence of the individual parameters of the reduced model on the flow-volume curve was evaluated by means of the sensitivity analysis. The conclusion is that the parameters of the scaling functions and elastic properties of lung tissue affect the measured data most significantly and that the descending part of the curve should be used to assess them.
机译：肺部的病理变化会改变强制呼气期间记录的流量曲线的形状。允许模拟测试结果的计算模型对于估计其参数而言过于复杂。在这项研究中，通过引入缩放气道特性的函数来简化复杂模型。通过敏感性分析评估了简化模型的各个参数对流量曲线的影响。结论是，肺组织的缩放函数和弹性特性的参数对测量数据的影响最大，应使用曲线的下降部分对其进行评估。

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