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Parts of the Problem of Polyploids in Rearrangement Phylogeny

机译:重排系统发育中多倍体问题的部分

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摘要

Genome doubling simultaneously doubles all genetic markers. Genome rearrangement phylogenetics requires that all genomes analyzed have the same set of orthologs, so that it is not possible to include doubled and unduplicated genomes in the same phylogeny. A framework for solving this difficulty requires separating out various possible local configurations of doubled and unduplicated genomes in a given phylogeny, each of which requires a different strategy for integrating ge-nomic distance, halving and rearrangement median algorithms. In this paper we focus on the two cases where doubling precedes a speciation event and where it occurs independently in both lineages initiated by a speciation event. We apply these to a new data set containing markers that are ancient duplicates in two yeast genomes.
机译:基因组加倍同时使所有遗传标记加倍。基因组重排系统发育学要求分析的所有基因组都具有相同的直系同源物,因此不可能在同一系统发育中包括双倍和未重复的基因组。解决此难题的框架要求在给定的系统发育中分离出双重和非重复基因组的各种可能的局部构型,每种构型都需要不同的策略来整合基因组距离,对分和重排中值算法。在本文中,我们关注在物种形成事件之前加倍并且在物种形成事件引发的两个谱系中独立发生的两种情况。我们将其应用于包含标记的新数据集,该标记是两个酵母基因组中的古代重复标记。

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