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首页> 外文会议>Italian Conference on Chemical and Process Engineering(ICheaP-6) vol.2; 20030608-11; Pisa(IT) >Density Distribution Surface Topography of Flat and Curved Tablets
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Density Distribution Surface Topography of Flat and Curved Tablets

机译：平板和曲面片的密度分布和表面形貌

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摘要

The axial and radial powder movements during the compaction process have been investigated using flat and curved faced punches for the axial strain applications. The density distributions in microcrystalline cellulose tablets were determined experimentally using a coloured layer technique and digital image analysis. Non -destructive topography measurements were taken to assess the variation in surface roughness of the tablets. Results showed that the tablets were non homogeneous with high density regions in the "top corners"(adjacent to the moving punch surface) and "middle bottom half for the flat faced tablets. High density regions were noted in the corners where the powder was in contact with the die wall for the curved faced tablets; both axial and radial powder movement were observed. Surface topography results also showed that the shape of tablets surfaces was relocated during unloading and ejection due to elastic recoil and stress relief.
机译：对于轴向应变应用，已经使用平面和曲面冲头研究了压实过程中粉末的轴向和径向运动。使用有色层技术和数字图像分析，通过实验确定了微晶纤维素片中的密度分布。进行非破坏性的形貌测量以评估片剂表面粗糙度的变化。结果表明，该片剂是不均匀的，在“顶角”（与移动的冲头表面相邻）和“平面片剂的中下半部”具有高密度区域。在粉末所处的角部注意到高密度区域。与曲面壁片剂的模具壁接触；观察到轴向和径向粉末运动；表面形貌结果还显示，由于弹性反冲和应力释放，片剂表面的形状在卸载和弹出过程中发生了重新定位。

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