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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >Ozone and Emergency Department Visit for Asthma in the Seven Metropolitan Cities in Korea 2013-2015: A Case-Crossover Study
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Ozone and Emergency Department Visit for Asthma in the Seven Metropolitan Cities in Korea 2013-2015: A Case-Crossover Study

机译：臭氧和急诊科2013-2015年在韩国七个大城市进行哮喘访问的病例交叉研究

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Harmful effects of exposure to ground-level ozone on exacerbation of existing respiratory condition are supported by number of studies in various countries. The objective of this study was to determine the association between ozone and emergency department (ED) visits for asthma in seven metropolitan cities (Seoul, Busan, Incheon, Daegu, Gwangju, Daejeon, and Ulsan) in Korea. Emergency department visit records by asthma (ICD10: J45 or J46) were obtained from National Emergency Department Information System for the period of 2013 to 2015. Air pollutants and meteorological data were obtained from the National Institute of Environmental Research and the Meteorological Administration. A time-stratified case-crossover design was used to analyze relationship between ozone and ED visits by asthma. Pooled estimates across the seven cities were calculated using a fixed-effect model. In total, 21,259 ED visits were included. Mean ambient concentrations of ozone were ranged from 34.98ppb for Seoul to 41.84ppb for Gwangju. Estimated odds ratios (ORs) of ozone on ED visit by asthma with an increment of 10ppb were ranged from 1.061 (95%CI: 1.032-1.091) for Seoul to 1.323 (95%CI: 1.146-1.527) for Ulsan with 3-days lag period. The stronger associations were found in younger population (age<19) and estimated ORs were ranged from 1.088(1.099-1.173) in Incheon to 1.602(1.280-2.005). Estimated pooled OR estimates were 1.073(95%CI: 1.052-1.095) for the total population, 1.129(95%CI: 1.091-1.168) for younger population (age<19), 1.060(95%CI: 1.028-1.093) for adult population (19<=age<65), and 1.021(95%CI: 0.980-1.063) for elderly population (age>=65). This study results provide the evidence that short-term exposure to ozone increases ED visit by asthma, especially for younger population.
机译：各国进行的许多研究都证明，接触地面臭氧对现有呼吸道疾病恶化的有害影响得到了支持。这项研究的目的是确定在韩国的七个大城市（首尔，釜山，仁川，大邱，光州，大田和蔚山），臭氧与急诊就诊与哮喘之间的关联。哮喘急诊就诊记录（ICD10：J45或J46）是从2013年至2015年国家急诊信息系统获得的。空气污染物和气象数据是从美国国家环境研究所和气象局获得的。采用时间分层的病例交叉设计来分析哮喘与臭氧就诊和急诊就诊之间的关系。使用固定效应模型计算了七个城市的汇总估算值。总共包括21,259次ED访问。平均臭氧浓度范围从首尔的34.98ppb到光州的41.84ppb。哮喘在急诊就诊时臭氧的估计比值比（ORs）为10ppb，首尔为1.061（95％CI：1.032-1.091），蔚山为期3天为1.323（95％CI：1.146-1.527）滞后期。在较年轻的人群（年龄<19）中发现了更强的关联，并且估计的OR范围从仁川的1.088（1.099-1.173）到1.602（1.280-2.005）。估计的总OR估计值为总人口1.073（95％CI：1.052-1.095），年轻人（年龄<19）的1.129（95％CI：1.091-1.168），1.060（95％CI：1.028-1.093）成人（19岁= 65岁）和1.021（95％CI：0.980-1.063）为老年人口（65岁以上）。这项研究结果提供了证据，表明短期暴露于臭氧会增加哮喘的急诊就诊率，尤其是对于年轻人。

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