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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >Health Benefits of Ozone Warning System in Three Major Cities of South Korea: A Regression Discontinuity Design
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Health Benefits of Ozone Warning System in Three Major Cities of South Korea: A Regression Discontinuity Design

机译：韩国三大城市臭氧预警系统的健康益处：回归中断设计

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Background: Ozone warning system is operating in cities of South Korea. The first stage warning is issued if 1-hour average of ground-level ozone exceeds 120 ppb. Using a case-crossover design combined with a regression discontinuity design (RDD), this study assessed whether the warning system provides health benefit Methods: Since ozone warnings are alerted independently over zones within a city and individuals were assumed to be exposed to ground-level ozone differently (e.g. due to outdoor activities), a fuzzy RDD was applied to estimate the causal effect of the first stage warning on hospital visits and hospitalizations for allergic rhinitis (J30), asthma (J45), pneumonia (J12-18) and chronic lower respiratory disease (J40-44) in three major cities of South Korea (Seoul, Busan, and Daegu) during the period of 2008-2013. Based on a time-stratified case-crossover design, we applied a conditional Poisson regression with over-dispersion. Temperature, relative humidity, holiday and influenza epidemic were adjusted for. Lag effects up to previous 5 days of exposure were considered. Results: A total of 30, 28, and 21 days exceeded 120 ppb of 1-hour maximum of ground-level ozone in Seoul, Busan, Daegu respectively. The first stage warning led to reductions (intent-to-treat effects) in hospital visits and hospitalizations for allergic rhinitis, asthma, pneumonia and chronic lower respiratory diseases. The decrements differed by the health outcomes and the cities, and ranged from 6.0% (95% CI: -0.6 to -11.1) in hospital visit for asthma in Seoul to 23.4% (95% CI: -0.18 to 41.5) in hospitalization for asthma in Busan. We also found evidence on some harvesting effects (i.e. increases of hospital visits and hospitalizations following the initial reductions by the warning). Conclusion: Ozone warning system in South Korea reduces hospital visits and hospitalizations for respiratory diseases.
机译：背景：臭氧警报系统正在韩国的城市中运行。如果地面臭氧的1小时平均值超过120 ppb，则发出第一​​阶段警告。本研究使用案例交叉设计与回归不连续性设计（RDD）相结合，评估了预警系统是否对健康有好处。方法：由于臭氧预警是在城市区域内独立发出的，因此假定个人暴露于地面臭氧有所不同（例如，由于户外活动所致），应用模糊RDD来评估第一阶段警告对变应性鼻炎（J30），哮喘（J45），肺炎（J12-18）和慢性病的就诊和住院的因果关系2008-2013年期间，韩国三个主要城市（首尔，釜山和大邱）发生了下呼吸道疾病（J40-44）。基于时间分层的案例交叉设计，我们应用了带有过度分散的条件Poisson回归。调节温度，相对湿度，假日和流行性感冒。考虑到暴露前5天的滞后效应。结果：首尔，釜山和大邱的总共30天，28天和21天分别超过了120 ppb的1小时最大臭氧水平。第一阶段的警告导致过敏性鼻炎，哮喘，肺炎和慢性下呼吸道疾病的住院就诊和住院减少（意向性治疗作用）。减少的幅度因健康结果和城市而异，首尔市的哮喘住院患者的减少幅度为6.0％（95％CI：-0.6至-11.1），首尔住院的23.4％（95％CI：-0.18至41.5）不等。釜山哮喘。我们还发现了一些收获效应的证据（即警告最初减少后，就诊和住院人数增加了）。结论：韩国的臭氧预警系统减少了因呼吸系统疾病而就诊和住院的人数。

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