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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >Different Coffee Products and Breast Cancer Risk among Hong Kong Chinese Women
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Different Coffee Products and Breast Cancer Risk among Hong Kong Chinese Women

机译：中国香港女性的咖啡产品不同和患乳腺癌的风险

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Background: Coffee contains caffeine and polyphenols that were reported to be able to low breast cancer risk, but the evidence from epidemiological studies remains inconsistent. Coffee products (i.e. instant, brewed) contain various levels of sugars and food additives, and thus their effects on breast cancer may vary and research on this area is lacking. This study aims to investigate the associations between coffee products and breast cancer risk among Hong Kong Chinese women. Methods: We conducted a hospital-based case-control study in three public hospitals, 1835 Chinese women (912 controls and 923 incident breast cancer cases) aged 24 to 84 years were consecutively recruited and interviewed using a standardized questionnaire including detailed information on coffee drinking. Results: There were no associations between overall coffee drinking and breast cancer risk. Interestingly, the association between instant coffee and breast cancer risk was contradicting to that of consuming coffee from restaurant. Compare to non-habitual coffee drinkers, women who drank > 1 cup(s) of instant coffee per day (adjust odds ratio (OR)=1.47, 95% confidence interval(CI)=1.02-2.11) was significantly associated with an increased risk of breast cancer after adjusting their age, body mass index, family history of breast cancer, educational level and shift work experiences. On the other hand, women who drank ≥ 1 cup(s) of coffee from restaurant/chain coffee per day (adjusted OR=0.34, 95% Cl= 0.12-0.94) was negatively associated with breast cancer risk. Conclusion: Coffee products under different processing methods may be a novel risk factor for breast cancer and further research is warranted.
机译：背景：咖啡中含有咖啡因和多酚，据报道它们可以降低患乳腺癌的风险，但是流行病学研究的证据仍然不一致。咖啡产品（即速溶咖啡，泡制咖啡）中含有各种含量的糖和食品添加剂，因此它们对乳腺癌的影响可能会有所不同，因此对此领域缺乏研究。这项研究旨在调查香港中国女性中咖啡产品与乳腺癌风险之间的关联。方法：我们在三家公立医院进行了一项基于医院的病例对照研究，连续招募了1835名年龄在24至84岁之间的中国妇女（912名对照和923名乳腺癌发生例），并使用包括关于饮酒的详细信息的标准化问卷进行了访谈。结果：喝咖啡与患乳腺癌的风险之间没有关联。有趣的是，速溶咖啡和患乳腺癌的风险之间的关联与从餐厅饮用咖啡的关联相反。与不习惯喝咖啡的人相比，每天喝超过1杯速溶咖啡的妇女（调整优势比（OR）= 1.47，95％置信区间（CI）= 1.02-2.11）与增加咖啡摄入量显着相关调整年龄，体重指数，乳腺癌家族史，受教育水平和轮班工作经验后患乳腺癌的风险。另一方面，每天从餐厅/链式咖啡中喝≥1杯咖啡的妇女（调整后的OR = 0.34，95％Cl = 0.12-0.94）与乳腺癌风险呈负相关。结论：不同加工方法下的咖啡产品可能是乳腺癌的新危险因素，值得进一步研究。

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