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首页> 外文会议>Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology >Associations between Ambient Air Temperature, Low Birth Weight and Small for Gestational Age in Term Newborns in Southern Israel
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Associations between Ambient Air Temperature, Low Birth Weight and Small for Gestational Age in Term Newborns in Southern Israel

机译：以色列南部足月新生儿的环境温度，低出生体重和小胎龄之间的关联

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Background: Relatively few studies have examined the association between extreme ambient air temperatures (Ta) and pregnancy outcomes. We investigated the association between Ta, term low birth weight (tLBW) and small for gestational age (SGA) in singleton term infants, using a decade (2004-2013) of regional hospital data in southern Israel. Methods: We linked all births in Soroka University Medical Center in the southern district of Israel and insured by Clalit Health Services with pregnancy Ta, estimated by a hybrid satellite-based spatio-temporally model. Analyses were adjusted for calendar month, year, maternal age, gravidity, parity, ethnicity, sex, poverty index and population density. Results: The study population included 56,141 newborns, with 1,716 (3.1%) cases of tLBW and 8,634 (15.4%) cases of SGA. The average and the median daily Ta across the entire pregnancy were 19.9 (range: 14.6-24.9) degrees centigrade. The lowest Ta quartile was associated with higher risk of tLBW (OR = 1.38, 95%CI 1.16-1.64) while the highest Ta quartile was not significantly associated with tLBW (OR = 1.12, 95%CI 0.96-1.32), in comparison to the two intermediate quartiles. In addition, the lowest Ta quartile was associated with significantly higher risk of SGA (OR = 1.18, 95%CI 1.09-1.28) while the highest quartile was associated with significantly lower risk of SGA (OR = 0.91, 95%CI 0.85-0.99). When examining associations among tLBW, SGA and trimester-specific Ta exposures, we found decreased risk of SGA with high Ta quartile during the 1st trimester (OR = 0.82, 95%CI 0.73-0.92), and increased risk for SGA with low Ta quartile during the 3rd trimester (OR = 1.17, 95%CI 1.05-1.31), while all other associations were not statistically significant. Conclusion: Ta is negatively associated with SGA in singleton term births, with increased risk in low Ta and decreased risk in high Ta.
机译：背景：相对较少的研究检查了极端环境空气温度（Ta）与妊娠结局之间的关系。我们使用以色列南部地区医院的十年（2004-2013年）数据，调查了单胎足月婴儿的Ta，足月低出生体重（tLBW）和胎龄小（SGA）之间的关联。方法：我们将以色列南部地区索罗卡大学医学中心的所有婴儿与由Clalit Health Services保险的孕妇Ta进行了关联，并通过基于卫星的时空混合模型对其进行了估计。对日历月，年，产妇年龄，妊娠，均等，种族，性别，贫困指数和人口密度进行了调整。结果：研究人群包括56,141例新生儿，其中1,716例（3.1％）tLBW病例和8,634例（15.4％）SGA病例。整个妊娠期间的平均每日Ta和中位数Ta为19.9（范围：14.6-24.9）摄氏度。与之相比，最低的Ta四分位数与较高的tLBW风险相关（OR = 1.38，95％CI 1.16-1.64），而最高的Ta四分位数与tLBW无显着相关性（OR = 1.12，95％CI 0.96-1.32）。两个中间四分位数。此外，最低的Ta四分位数与SGA的风险显着较高相关（OR = 1.18，95％CI 1.09-1.28），而最高的四分位数与SGA的风险显着较低相关（OR = 0.91，95％CI 0.85-0.99 ）。在检查tLBW，SGA和特定于Ta的Ta暴露之间的关联时，我们发现在第三个三个月中具有高Ta四分位的SGA风险降低（OR = 0.82，95％CI 0.73-0.92），而具有低Ta四分位的SGA风险增加在孕晚期（OR = 1.17，95％CI 1.05-1.31），而所有其他关联均无统计学意义。结论：单胎足月出生的Ta与SGA呈负相关，低Ta的风险增加而高Ta的风险降低。

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