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首页> 外文会议>Journal of Organ Dysfunction: ISRD 2007 Abstract Book >Quantitative ventilation/perfusion SPECT is diagnostic in pulmonary embolism and other diseases
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Quantitative ventilation/perfusion SPECT is diagnostic in pulmonary embolism and other diseases

机译：定量通气/灌注SPECT可诊断肺栓塞和其他疾病

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Aim: To apply holistic interpretation criteria, including ancillary scintigraphic findings and tomography of ventilation/perfusion SPECT (V/P <,SPECT>) with respect to PE and other lung diseases. Method: Ventilation starts with inhalation of 30MBq <'99m>Tc- Technegas<'R>, immediately followed by an i.v. injection of 120MBq <'99m>TcMAA for the perfusion study. The patient is in the supine position immobilized during the 20 minutes acquisition for both studies. Interpretation: Images can be presented in frontal, sagittal and transversal slices. Volume rendered images allow simultaneous rotation of 3D views. V/P quotient images facilitate quantification and identification of V/P mismatches typical for PE diagnosis. Result: V/P<,SPECT> has been routinely performed in about 6000 patients with suspected PE from period April 2002 to October 2006. Ventilation studies, essential for lung delineation greatly contributes to the recognition of peripheral perfusion defects typical for PE. They explain perfusion defects of different nature such as heart failure, obstructive diseases and parenchymal changes as pneumonia. New standardized technique together with holistic interpretation reduced the rate of nondiagnostic reports to the level of 1%. Ancillary findings were reported in 45% of patients. PE was identified in 23%. Conclusion: The low cost and the short time for study completion are attractive. V/P SPECT can be performed in any patient, without the burden of contrast and with minimal radiation exposure. It offers a first hand method for diagnosis of PE and provides information about heart failure, obstructive disease, parenchymal processes. Since the extension of PE is well quantified, it is invaluable for the decision of outpatient therapy in selected patients and for their follow up. In 2004 until 2006, 375 patients with up to 40% of PE extension were treated at home. That saves about 2000 euro per patient. No complication related to home treated has occurred.
机译：目的：应用整体解释标准，包括关于PE和其他肺部疾病的辅助闪烁显像和通气/灌注SPECT断层扫描（V / P <，SPECT>）。方法：通风从吸入30MBq <'99m> Tc- Technegas <'R>开始，然后立即进行静脉输注。注射120MBq <99m> TcMAA用于灌注研究。在两项研究中，患者在20分钟内都处于固定的仰卧位。解释：图像可以正面，矢状和横切面显示。体积渲染图像允许同时旋转3D视图。 V / P商图像有助于量化和识别PE诊断中典型的V / P不匹配。结果：从2002年4月至2006年10月，已对大约6000例可疑PE患者常规进行了V / P <，SPECT>。通气研究对肺部描记至关重要，这有助于识别PE典型的外周血灌注缺陷。他们解释了不同性质的灌注缺陷，例如心力衰竭，阻塞性疾病和肺炎等实质性改变。新的标准化技术和整体解释将非诊断性报告的比率降低到了1％。据报道45％的患者有辅助检查结果。 PE占23％。结论：低成本和短时间完成研究具有吸引力。 V / P SPECT可以在任何患者中进行，而无需增加造影剂的负担，并且可以将放射线辐射降至最低。它提供了诊断PE的第一手方法，并提供了有关心力衰竭，阻塞性疾病，实质过程的信息。由于PE的扩展已被很好地量化，因此对于决定所选患者的门诊治疗以及对其随访至关重要。从2004年到2006年，有375例PE延伸率高达40％的患者在家中接受治疗。每位患者节省约2000欧元。没有发生与家庭治疗有关的并发症。

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