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首页> 外文会议>Lasers in Urology, Gynecology, and General Surgery >In-vitro and clinical evaluation of transurethral laser-induced prostatectomy (TULIP)
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In-vitro and clinical evaluation of transurethral laser-induced prostatectomy (TULIP)

机译：经尿道激光诱导前列腺切除术（TULIP）的体外和临床评估

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Abstract: Transurethral ultrasound-guided laser induced prostatectomy (TULIP) is a recent development in the treatment of benign prostatic hyperplasia. The system is based upon Nd:YAG laser irradiation delivered by a right angled fiber. The dosimetry used in a clinical situation is mostly based upon animal studies. In this study, the light and temperature distribution in the prostate during Nd:YAG laser irradiation were modeled using Monte Carlo and finite differences theory. The results of this model were compared with in vitro experiments. The influence of the different parameters involved, e.g., the scanning speed and the power of the laser beam, were evaluated. Initial results show the temperature distribution and thus the therapeutic effect of the TULIP procedure. Until now 36 patients have been treated successfully. The mean in-hospital time was somewhat shorter than for a TURP treatment while the results were comparable. These treatments, however, show the need for a better understanding of the mechanisms involved. Modeling and subsequent in vitro and in vivo measurements might improve the understanding and safe and successful application of prostate treatment using laser based systems. !14
机译：摘要：经尿道超声引导的激光诱导前列腺切除术（TULIP）是治疗良性前列腺增生的最新进展。该系统基于直角光纤传输的Nd：YAG激光辐射。临床情况下使用的剂量测定法主要基于动物研究。在这项研究中，使用Monte Carlo和有限差分理论对Nd：YAG激光照射期间前列腺中的光和温度分布进行建模。该模型的结果与体外实验进行了比较。评估了所涉及的不同参数的影响，例如扫描速度和激光束功率。初步结果显示了温度分布以及TULIP程序的治疗效果。迄今为止，已经成功治疗了36名患者。平均住院时间略短于TURP治疗，但结果可比。但是，这些处理方法表明需要更好地了解所涉及的机制。对基于激光的系统进行建模以及随后的体外和体内测量可能会增进对前列腺治疗的了解和安全成功的应用。 ！14

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