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Therapeutic aspects of endoscopic ultrasound

机译:内窥镜超声的治疗方面

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摘要

Abstract: Endoscopic ultrasound (EUS) is a technology that had been used primarily as a passive imaging modality. Recent advances have enabled us to move beyond the use of EUS solely as a staging tool to an interventional device. Current studies suggest that interventional applications of EUS will allow for minimally invasive assessment and therapies in a cost-effective manner. Endoscopic ultrasound with fine needle aspiration (EUS-FNA) has been demonstrated to be a technically feasible, relatively safe method of obtaining cytologic specimens. The clinical utility of EUS- FNA appears to be greatest in the diagnosis and staging of pancreatic cancer and in the nodal staging of gastrointestinal and pulmonary malignancies. In addition, EUS-FNA has demonstrated utility in the sampling pleural and ascitic fluid not generally appreciated or assessable to standard interventions. Interventional applications of EUS include EUS-guided pseudocyst drainage, EUS-guided injection of botulinum toxin in the treatment of achalasia, and EUS- guided celiac plexus neurolysis in the treatment of pancreatic cancer pain. Finally, EUS-guided fine-needle installation is being evaluated, in conjunction with recent bimolecular treatment modalities, as a delivery system in the treatment of certain gastrointestinal tumors. !36
机译:摘要:内窥镜超声(EUS)是一种主要用作被动成像方式的技术。最近的进展使我们能够从仅将EUS用作分期工具,而不再是介入设备。当前的研究表明,超声内镜的介入治疗将以经济有效的方式进行微创评估和治疗。内镜超声与细针穿刺术(EUS-FNA)已被证明是一种技术可行,相对安全的获取细胞学标本的方法。 EUS-FNA在胰腺癌的诊断和分期以及胃肠道和肺部恶性淋巴结的分期中似乎具有最大的临床效用。此外,EUS-FNA已证明在取样胸膜和腹水中具有实用性,但通常无法通过标准干预措施进行评估或评估。 EUS的介入应用包括EUS引导的假性囊肿引流,EUS引导的肉毒杆菌毒素注射治疗门失弛缓症和EUS引导的腹腔神经丛神经溶解治疗胰腺癌疼痛。最后,结合最近的双分子治疗方法,正在评估EUS引导的细针安装,作为治疗某些胃肠道肿瘤的递送系统。 !36

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