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Model-based optimization of Medical Test Strips

机译：基于模型的医学测试条优化

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Medical Test Strips made from plastics can provide a cheap and reliable analysis of body liquids. The underlying microsystem contains structured micro-channels to adjust the filling time as an important parameter for chemical reactions. Columns or lamellae of some μm dimensions are placed in the channel to define the fluidic resistance, which is influenced by the pitch between these structure elements as well as by their shape. As no analytic solution exists to describe the microfluidic interaction, the authors have been following approaches based on discrete partial differential equations and behavioural descriptions to obtain a simulation model. Model-based optimization has been performed to get useful sets of parameters to be handed to the industrial partner for manufacturing and therefore verification of the calculated results.
机译：用塑料制成的医学测试条可以对体液进行廉价而可靠的分析。底层微系统包含结构化的微通道，可将填充时间调整为化学反应的重要参数。将一些μm尺寸的圆柱或薄片放置在通道中以定义流体阻力，该阻力受这些结构元素之间的间距及其形状的影响。由于不存在描述微流体相互作用的解析方法，因此作者一直遵循基于离散偏微分方程和行为描述的方法来获得仿真模型。已执行基于模型的优化，以获取有用的参数集，以将其传递给工业合作伙伴进行制造，从而验证计算结果。

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